Patients with intertriginous, anogenital or facial psoriasis see significant clinical improvements with the use of crisaborole 2% ointment, a nonsteroidal phosphodiesterase 4 inhibitor, according to the results of a study. The topical agent is also well tolerated.
Individuals with persistent acne present with significant hyperandrogenism, polycystic ovary syndrome and hormonal abnormalities—conditions that require an endocrinological evaluation—a study has found.
Treatment with antiepileptic drugs does not increase the risk of skin cancer, but an association has been observed between use of carbamazepine and lamotrigine and squamous cell carcinoma (SCC), a recent study has shown.
Poorly differentiated cutaneous squamous cell carcinomas (cSCCs) are likely to be incompletely excised in peripheral and deep planes, despite adherence to the British Association of Dermatology-British Association of Plastic, Reconstructive and Aesthetic Surgery guidelines, reports a recent UK study.
Topical immunotherapy with squaric acid dibutylester appears to be effective in the treatment of alopecia areata, according to a study, lending support to current treatment guidelines recommending the use of topical immunotherapies.
Placebo responses appear to be common in randomized controlled trials for atopic dermatitis, reports a new meta-analysis. Better methodological control, such as double- or triple-blinding and more balanced sex distributions, may help address this.
Treatment with tumour necrosis factor-alpha (TNFα) inhibitor may likely lead to an increase in body weight and body mass index (BMI) in patients with psoriasis, whereas treatment with anti-interleukin (IL)-12/23 and IL-17 biologics does not, results of a recent systematic review and meta-analysis have shown.
A bidirectional association exists between alopecia areata (AA) and major depressive disorder (MDD) among probands and unaffected siblings, reveals a study. This suggests that shared familial mechanisms tend to cause AA and MDD.