A phase I, single-centre, open-label study has found that repeated intravenous infusions of KHK4083, an investigational human monoclonal antibody, is sufficiently safe and clinically effective for the treatment of moderate to severe atopic dermatitis (AD).
Use of dipeptidyl-peptidase 4 (DPP-4) inhibitors is linked to the development of bullous pemphigoid, although the risk increase appears to be limited to linagliptin, according to the results of a meta-analysis.
Patients with cancer who are receiving vascular endothelial growth factor receptor–tyrosine kinase inhibitors (VEGFR-TKIs) are at increased risk of developing hand-foot skin reaction (HFSR), results of a recent meta-analysis have shown.
Adherence to current surveillance guidelines, such as routine skin examination and photoprotection recommendations, is essential among survivors of haematopoietic cell transplantation (HCT) at highest risk for the development of cutaneous melanoma, suggests a recent study.
The risk of new-onset inflammatory bowel disease (IBD) among patients with psoriasis exposed to interleukin-17 inhibitor (IL-17i) appears to be comparable to that among unexposed individuals, suggests a study. In addition, the incidence of IBD in exposed patients is low.
A picosecond alexandrite laser (PSAL) appears to be superior to Q-switched alexandrite laser (QSAL) for the treatment of nevus of Ota, as shown by its better clinical results and fewer adverse events, according to a study.
In patients with heart failure with reduced ejection fraction (HFrEF) receiving angiotensin-converting-enzyme (ACE) inhibitors, high dosing confers benefits for the risk of death or hospitalization that are similar to that obtained with lower dosing, according to a systematic review and meta-analysis.
Osteoarthritis (OA) is the most common condition affecting the joints. Dr Lee Eu Jin, an Orthopaedic Surgeon from Liberty Orthopaedic Clinic at Mount Elizabeth Medical Centre, Singapore, shares his insights with Pearl Toh on how to manage OA in the primary care setting.