Use of a single-agent temozolomide appears to be an effective alternative to late adjuvant therapy in patients with melanoma if novel treatments, such as targeting and immune therapies, are not available, suggests a recent study.
Hospitalized cancer patients with rash and elevated interleukin (IL)-6 and tumour necrosis factor (TNF)-α have a sixfold increased risk of mortality over the course of follow-up, according to a recent study.
There appears to be a low incidence of inflammatory bowel disease (IBD) among patients with acne vulgaris (AV) exposed to isotretinoin, according to a recent study. Additionally, the risk is similar to that for unexposed patients with AV.
In patients with moderate-to-severe psoriasis, biologic agents seem to reduce mortality risk regardless of treatment duration, a recent study has found. Methotrexate, on the other hand, only shows a similar efficacy when used for at least a year.
A treatment algorithm is needed for tumour necrosis factor-α (TNF-α) inhibitor (TNFI)-induced psoriasis, suggests a study with a cohort representing the largest single-institution group of patients with TNFI-induced psoriasis diagnosed and managed or comanaged by dermatologists to date.
Prenatal exposure to tobacco is associated with an increased risk of paediatric psoriasis in a monotonic fashion, which suggests that smoking may contribute to psoriasis pathogenesis, suggest the results of a recent study.
Dr. Hsu Li Yang, Dr. Tan Thuan Tong, Dr. Andrea Kwa,
08 Jan 2021
Antimicrobial resistance has become increasingly dire as the rapid emergence of drug resistance, especially gram-negative pathogens, has outpaced the development of new antibiotics. At a recent virtual symposium, Dr Hsu Li Yang, Vice Dean (Global Health) and Programme Leader (Infectious Diseases), NUS Saw Swee Hock School of Public Health, presented epidemiological data on multidrug-resistant (MDR) gram-negative bacteria (GNB) in Asia, while Dr Tan Thuan Tong, Head and Senior Consultant, Department of Infectious Diseases, Singapore General Hospital (SGH), focused on the role of ceftazidime-avibactam in MDR GNB infections. Dr Andrea Kwa, Assistant Director of Research, Department of Pharmacy, SGH, joined the panel in an interactive fireside chat, to discuss challenges, practical considerations, and solutions in MDR gram-negative infections. This Pfizer-sponsored symposium was chaired by Dr Ng Shin Yi, Head and Senior Consultant of Surgical Intensive Care, SGH.
Spending too much time sitting cannot be good for the body, and rising to one's feet breaks up such a behaviour and yields small, but meaningful, reductions in certain cardiovascular disease (CVD) risk factors, according to the results of a meta-analysis.
Use of thyroid hormone therapy does not seem to protect older adults with subclinical hypothyroidism against mortality, but it appears to confer survival benefits to those aged <65 years, results of a study have shown.