Among older patients with chronic low back pain and depression who are treated with venlafaxine, exposure to opioids is associated with reduced likelihood of achieving early pain response but not that of attaining the combined pain/depression outcome, a study has shown.
Routine prescription of a hypnotic medication does not appear to substantially reduce suicidal ideation in depressed outpatients with insomnia, but coprescription of such drug during antidepressant initiation may help suicidal outpatients, particularly those with severe insomnia, suggest the results of a study.
Depressive symptoms appear to be common in middle aged and older Chinese adults, particularly in women and those residing in rural areas, according to a secondary analysis of a prospective cohort study. On the other hand, longer sleep duration and better self-perceived health status confer protective benefits.
Mental health smartphone applications (apps) help improve a range of outcomes, including depressive and generalized anxiety symptoms and stress levels, with small-to-moderate effect sizes, according to a meta-analysis.
Binge drinking in Singapore is less prevalent than internationally, and most binge drinkers engage in the practice only now and then, as reported in a recent study. Despite this trend, binge drinking is associated with a myriad of mental health conditions and reduced quality of life.
Switching from a tricyclic antidepressant to a selective serotonin reuptake inhibitor or the other way around, following failure of or side-effects to the first antidepressant appears to be a viable strategy to achieve response among patients with major depressive disorder, a study has found.
Patients with major depression appear to exhibit small reductions in several measures of heart rate variability, and these alterations may potentially predict poor cardiovascular health outcomes among those without known cardiovascular disease, according to the results of a meta-analysis.