Switching from a tricyclic antidepressant to a selective serotonin reuptake inhibitor or the other way around, following failure of or side-effects to the first antidepressant appears to be a viable strategy to achieve response among patients with major depressive disorder, a study has found.
Patients with major depression appear to exhibit small reductions in several measures of heart rate variability, and these alterations may potentially predict poor cardiovascular health outcomes among those without known cardiovascular disease, according to the results of a meta-analysis.
More than three-fourths of people with mood, anxiety and alcohol use disorder in Singapore receive no treatment for their condition, reflecting a high treatment gap in mental healthcare that has remained a matter of concern for years now, according to data from the 2016 Singapore Mental Health Study.
Eating healthy foods, especially those following the Mediterranean dietary pattern, or avoiding proinflammatory diet appears to exert a protective effect on the risk of depression, according to a systematic review and meta-analysis.
Esketamine nasal spray effectively and rapidly improves depressive symptoms in patients with treatment-resistant depression, making it the first antidepressant to be approved by the US FDA in a new drug class.
Polycystic ovary syndrome (PCOS) appears to be associated with increased depression, anxiety and perceived stress, with stress potentially mediating the observed relationship with depression and anxiety, according to a study.
Aripiprazole augmentation early in treatment is useful for inducing response in major depressive disorder, although caution should be exercised when increasing the dose to >6 mg/day, a study has shown.
The levels of depression biomarkers in healthy postmenopausal women were lower after 8 weeks of increased daily physical activity, suggesting that the intervention may prevent depression in older people.