Dengue News

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Revised guideline for severe dengue averts death, but not organ failure

Stephen Padilla, 20220310120000

Following the revised guideline for severe dengue (SD), which includes intensive monitoring of vital signs among others, helps prevent death of patients with multiorgan failure and/or abdominal compartment syndrome (ACS), but not organ failure, a study has shown.

Probiotic consumption linked to reduced duration of dengue symptoms

Pank Jit Sin, 20211125033145

Consumption of a specific probiotic has been linked to reductions in dengue symptoms, a new study reveals.

Certain signs, symptoms in early dengue may predict disease progression

Roshini Claire Anthony, 20210705160001

Certain signs such as low platelet counts and serum albumin levels, and symptoms like vomiting and abdominal pain during the early, febrile phase of dengue may predict progression to severe disease, according to a systematic review and meta-analysis.

Dengue infection tied to raised leukaemia risk

Roshini Claire Anthony, 20200309140103

Individuals with a history of dengue infection may have a twofold risk of developing leukaemia 3–6 years post-infection, according to a population-based cohort study from Taiwan.

Statins not protective against dengue in infected patients with hyperlipidaemia

Jairia Dela Cruz, 20181129110000

Statins appear to confer no benefit for dengue severity in patients with hyperlipidaemia, according to a Singapore study.

Construction sites an important contributor to dengue transmission

Jairia Dela Cruz, 20180817100000

Spillover transmission of dengue viruses from construction sites is highly likely to occur and is critical for the surrounding residential areas, according to a Singapore study.

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SARS-CoV-2 Variants: Everything you need to know

01 Feb 2023

The COVID-19 pandemic continues to evolve with the emergence of new SARS-CoV-2 variants. The variants of concern have the potential to impact the transmissibility, virulence, and clinical presentation of the disease, affecting the epidemiology, public health measures, and diagnostic and therapeutic options. Mutations in the spike protein of the virus have increased its ability to infect humans and evade neutralization by natural or immunisation-induced antibodies. The highly mutated Omicron variant of SARS-CoV-2 has multiple sublineages with varying transmissibility and immune evasion potential. Pre-exposure prophylaxis plays a crucial role in protecting the immunocompromised populations against severe disease; however, the rapidly changing landscape of the variants poses a major challenge to the current and future effectiveness of pre-exposure prophylactic monoclonal antibodies.

Timely treatment of patients at risk for severe COVID-19 prevents severe outcomes

Dr. Asok Kurup, Dr. Alex Soriano, 31 Oct 2022

Despite widespread uptake of vaccinations, COVID-19 remains a serious health issue for high-risk patients, owing to the emergence of new variants of concern (VOCs), waning immunity, and breakthrough infections.

At a recent symposium in Singapore, esteemed experts Dr Asok Kurup, Consultant Infectious Diseases Physician at Mount Elizabeth Medical Centre, Singapore, and Dr Alex Soriano, Head of Infectious Diseases Department, Hospital Clínic of Barcelona and Assistant Professor, University of Barcelona, Spain, gave insights on the evolution of global trends since the start of the COVID-19 pandemic and discussed key challenges in managing high-risk patients with COVID-19 in the ICU. They also highlighted early treatment strategies to minimize the burden of COVID-19 on healthcare systems.