Differential Diagnosis

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CROUP

Croup is a viral infection that causes erythema and edema of the tracheal walls and narrowing of the subglottic region. It is often characterized by an acute, rapidly progressing respiratory disease.
It is a medical emergency in children and requiring immediate treatment.
Most common causes are parainfluenza virus 1&2 and respiratory syncytial virus.
Occurrence of symptoms is usually at night and with abrupt onset and improve during daytime.

Diagnosis

Diphtheria

Characterized by malaise, sore throat, anorexia, & low-grade fever
Within 2-3 days, pharyngeal exam may show a typical gray-white membrane adherent to the tissue that bleeds when attempted to be removed
With insidious course but sudden respiratory obstruction may occur

Epiglottitis

Characterized by sudden onset of high fever, dysphagia, drooling & anxious appearance
Patient prefers to sit forward in sniffing position
Barking cough is rarely observed

Tracheitis

Patient appears febrile, toxic & gives poor response to Epinephrine

Other Causes of Stridor

Foreign body
Retropharyngeal abscess
Hereditary angioedema

Searches for unproven COVID-19 therapies spike after high-profile endorsements

Roshini Claire Anthony, 18 Jun 2020

Endorsement of unproven COVID-19 treatments by high-profile public figures led to a drastic increase in the search and purchase of said treatments in the US, according to a research letter published in JAMA.

Gut dysbiosis in COVID-19 prompts development of probiotic supplement

Christina Lau, 23 Jun 2020

Patients with coronavirus disease 2019 (COVID-19) have significant gut dysbiosis that persists even after viral clearance and resolution of respiratory symptoms, according to a metagenomic study by the Chinese University of Hong Kong (CUHK). These findings have led to the development of a probiotic supplement expected to be available in a few months.