contact%20dermatitis
CONTACT DERMATITIS

Contact dermatitis is an inflammation of the skin that can be acute or chronic that manifests as eczematous dermatitis due to exposure to substances in the environment.

Allergic contact dermatitis is an immunologic cell-mediated skin reaction to exposure to antigenic substances.
The lesions initially appear on the cutaneous site of principal exposure then may spread to other more distant sites due to contact or autosensitization. Lesions are typically asymmetrical and unilateral.
Specific signs and symptoms will depend on the duration, location, degree of sensitivity and concentration of allergens. The patch test shows reaction to allergen.
Irritant contact dermatitis is a non-immunologic skin reaction to skin irritants.
It is often localized to areas of thin skin eg eyelids, intertriginous areas.

Definition

  • Any skin disorder brought about by contact w/ an exogenous substance that triggers an allergic &/or irritant response

Signs and Symptoms

Allergic Contact Dermatitis
  • Initially, lesions appear on the cutaneous site of principal exposure; may spread to other more distant sites due to contact or autosensitization
  • Lesions are typically asymmetrical & unilateral
  • Specific signs & symptoms will depend on the duration, location, degree of sensitivity & concentration of allergens
  • Patch test shows reaction to allergen
Acute Allergic Contact Dermatitis
  • Acute eruptions present w/ macular erythema, papules, vesicles & bullae
Chronic Allergic Dermatitis
  • Lesions are usually lichenified, scaling, fissures w/ or without vesicles
  • Pigmentary changes can occur
Irritant Contact Dermatitis
  • Prone to irritation from chemical substances are the face, dorsum of the hands, finger webs, palms, soles or back
Acute Irritant Contact Dermatitis
  • Acute lesions are painful, edematous, erythematous, weepy & vesicular
  • There is associated sensation of burning, stinging or pain in the site of contact to irritant
  • Usually results from a single exposure to an irritant or caustic chemical
Chronic Irritant Contact Dermatitis
  • Chronic lesions are dry, erythematous, scaling, fissuring, cracked & lichenified
  • Hardening & adaptation of the skin may occur due to repeated contact w/ irritants

 

Risk Factors


Common Trigger Factors

  • Allergic Contact Dermatitis
    • Medications, certain plants, metals, foods, fragrances, stabilizers in skin products, preservatives, etc 
  • Irritant Contact Dermatitis
    • Strong alkaline soaps, organic solvents, acid, chlorinated or bleach type ingredients, inhalants, airborne chemicals, etc

Location of inflammation may suggest trigger factors for Allergic Contact Dermatitis & Irritant Contact Dermatitis

  • Eg scalp & ears
    • Possible trigger factors: Shampoo, hair dyes, topical medication, spectacles, metal earrings, etc

Allergic Contact Dermatitis & Irritant Contact Dermatitis may be related to occupational exposure

  • Exposure to cement, epoxy, glues, paint & solvents may trigger allergic contact dermatitis
  • Fuels, lubricants & cement may trigger irritant contact dermatitis
Editor's Recommendations
Most Read Articles
4 days ago
Older women with longer endogenous oestrogen exposure and hormone therapy use are at much higher odds of having favourable cognitive status in late life, a recent study suggests.
2 days ago
In patients with atrial fibrillation (AF) and stable coronary artery disease (CAD), rivaroxaban monotherapy is noninferior to combination treatment with an antiplatelet therapy in terms of cutting the risk of cardiovascular events and mortality, according to data from the AFIRE trial.
Elvira Manzano, 3 days ago
Supplementation with omega-3 fatty acids or vitamin D3 for up to 5 years has no effect on kidney function in adults with type 2 diabetes (T2D), the VITAL-DKD* ancillary study has shown.
Jairia Dela Cruz, 18 hours ago
Many patients with nonvalvular atrial fibrillation (NVAF) in Thailand use anticoagulants, but the uptake of nonvitamin-K oral anticoagulants remains suboptimal despite showing an upward trend, according to data from the COOL-AF registry presented at the European Society of Cardioloy (ESC) Asia Congress 2019 with APSC and AFC.