contact%20dermatitis
CONTACT DERMATITIS
Treatment Guideline Chart

Contact dermatitis is an inflammation of the skin that can be acute or chronic that manifests as eczematous dermatitis due to exposure to substances in the environment.

Allergic contact dermatitis is an immunologic cell-mediated skin reaction to exposure to antigenic substances.
The lesions initially appear on the cutaneous site of principal exposure then may spread to other more distant sites due to contact or autosensitization. Lesions are typically asymmetrical and unilateral.
Specific signs and symptoms will depend on the duration, location, degree of sensitivity and concentration of allergens. The patch test shows reaction to allergen.
Irritant contact dermatitis is a non-immunologic skin reaction to skin irritants.
It is often localized to areas of thin skin eg eyelids, intertriginous areas.

Contact Dermatitis References

  1. Belsito DV. The diagnostic evaluation, treatment, and prevention of allergic contact dermatitis in the new millennium. J Allergy Clin Immunol. 2000 Mar;105(3):409-420. PMID: 10719287
  2. Blauvelt A, Huang ST, Udey MC. Allergic and immunologic diseases of the skin. J Allergy Clin Immunol. 2003 Feb;111(2 Suppl):S560-S570. PMID: 12592302
  3. Bruckner AL, Weston WL. Allergic contact dermatitis in children: a practical approach to management. Skin Ther Lett. 2002 Oct;7(8):3-5. PMID: 12548328
  4. Drake LA, Dorner W, Goltz RW, et al. Guidelines of care for contact dermatitis. J Am Acad Dermatol. 1995 Jan;32(1):109-113. http://www.ncbi.nlm.nih.gov/pubmed/?term=7822498. PMID: 7822498
  5. Fyhrquist-Vanni N, Alenius H, Lauerma A. Contact dermatitis. Dermatol Clin. 2007 Oct;25(4):613-623. http://www.ncbi.nlm.nih.gov/pubmed/?term=17903620. PMID: 17903620
  6. Leung D, Schatz M. Consultation and referral guidelines citing the evidence: how the allergist-immunologist can help. J Allergy Clin Immunol. 2006 Feb;117(Suppl 2 Suppl Consultation):S495-S523. http://www.jacionline.org/article/S0091-6749(05)02579-0/pdf. PMID: 16553071
  7. Kennedy MS. Comprehensive care in the allergy/asthma office: evaluation of chronic eczema and urticaria and angioedema. Immunol Allergy Clin North Am. 1999;19(1):19-33
  8. Heymann WR. Hand dermatitis. J Am Acad Dermatol. 2006 Jun;54:1078-1080. http://www.jaad.org/article/S0190-9622(06)00324-0/pdf. PMID: 16713475
  9. Mark BJ, Slavin RG. Allergic contact dermatitis. Med Clin North Am. 2006 Jan;90(1):169-185. http://www.ncbi.nlm.nih.gov/pubmed/?term=Mark+BJ%2C+Slavin+RG%09Allergic+contact+dermatitis. PMID: 16310529
  10. Lushniak BD. Occupational skin diseases. Prim Care. 2000 Dec;27(4):895-916. PMID: 11072293
  11. Ong PY, Boguniewicz M. Atopic dermatitis and contact dermatitis in the emergency department. Clin Pediatr Emerg Med. 2007;8(2):81-86. http://www.clinpedemergencymed.com/article/S1522-8401(07)00023-7/pdf.
  12. Peate WE. Occupational skin disease. Am Fam Physician. 2002 Sep;66(6):1025-1032. PMID: 12358214
  13. Scalf L, Genebriera J, Davis MD, et al. Patients' perceptions of the usefulness and outcome of patch testing. J Am Acad Dermatol. 2007 Jun;56(6):928-932. PMID: 17239988
  14. Peralejo B, Beltrani V, Bielory L. Dermatologic and allergic conditions of the eyelid. Immunol Allergy Clin North Am. 2008 Feb;28(1):137-168. doi: 10.1016/j.iac.2007.12.004. PMID: 18282550
  15. Weston WL, Bruckner AL. Allergic contact dermatitis. Clin North Am. 2000;47(4):894-907
  16. Swerlick RA, Lawley TJ. Eczema, psoriasis, cutaneous infection, acne and other common skin disorders. The McGraw-Hill Companies. http://harrisons.accessmedicine. com
  17. Habif TP. Contact dermatitis and patch testing. Clinical Dermatology. 5th ed. Pennsylvania: Mosby, Elsevier; 2010
  18. Habif TP. Contact dermatitis and patch testing. In: Habif TP. Clinical dermatology: A color guide to diagnosis and therapy. 4th. Philadelphia, PA: Mosby, Elsevier; 2004.
  19. Schalock PC, Zug KA. Contact Dermatitis. In: Rakel RE, Bope ET. Conn's Current Therapy. 60th ed. Philadelphia: Saunders, an imprint of Elsevier; 2008
  20. Morelli JG. Eczematous disorders. In: Behrman RE, Kliegman RM, Jenson HB, eds. Nelson textbook of Pediatrics. 18th ed. Philadelphia: Saunders, Elsevier; 2007
  21. Ferri FF. Dermatitis, contact. In: Ferri FF. Ferri’s clinical advisor: instant diagnosis and treatment. 1st ed. Philadelphia, PA: Mosby, Elsevier; 2008.
  22. MedWormhttp://www.medworm.com/rss/index.php/Allergy-%26-Immunology/3/http://www.medworm.com/rss/medicalfeeds/specialities/Allergy-Immunology.xml
  23. MedWorm http://www.medworm.com/rss/index.php/Dermatology/12/ http://www.medworm.com/rss/medicalfeeds/specialities/Dermatology-News.xml
  24. MedWormhttp://www.medworm.com/rss/index.php/Pediatrics/33/http://www.medworm.com/rss/medicalfeeds/specialities/Pediatrics.xml
  25. Tan CH, Rasool S, Johnston GA. Contact dermatitis: Allergic and irritant. Clin Dermatol. 2014 Jan;32(1):116-124. www.cidjournal.com/article/S0738-081X(13)00100-4/pdf. PMID: 24314385
  26. Usatine RP, Riojas M. Diagnosis and management of contact dermatitis. Am Fam Physician. 2010 Aug;82(3):249-255. http://www.aafp.org/afp/2010/0801/p249.pdf. Accessed 02 May 2014. PMID: 20672788
  27. Fonacier L, Bernstein DI, Pacheco K, et al; American Academy of Allergy, Asthma & Immunology; American College of Allergy, Asthma & Immunology; Joint Council of Allergy, Asthma & Immunology. Contact dermatitis: a practice parameter-update 2015. J Allergy Clin Immunol Pract. 2015 May;3(Suppl 3):S1-S39. https://www.aaaai.org/Aaaai/media/MediaLibrary/PDF%20Documents/Practice%20and%20Parameters/Contact-dermatitis-2015.pdf. Accessed 13 Apr 2016. PMID: 25965350
  28. Johansen JD, Aalto-Korte K, Agner T, et al. European Society of Contact Dermatitis guideline for diagnostic patch testing - recommendations on best practice. Contact Dermatitis. 2015 Oct;73(4):195-221. http://onlinelibrary.wiley.com/doi/10.1111/cod.12432/epdf. PMID: 26179009
  29. Brod BA. Management of allergic contact dermatitis. UpToDate. www.uptodate.com. Feb 2018.
  30. Goldner R. Irritant contact dermatitis in adults. UpToDate. www.uptodate.com. Aug 2018.
  31. Johnston GA, Exton LS, Mohd Mustapa MF, et al. British Association of Dermatologists' guidelines for the management of contact dermatitis 2017. Br J Dermatol. 2017 Feb;176(2):317-329. doi: 10.1111/bjd.15239. PMID: 28244094
  32. Schalock PC, Dunnick CA, Nedorost S, et al. American Contact Dermatitis Society core allergen series. Dermatitis. 2013 Jan;24(1):7-9. doi: 10.1097/DER.0b013e318281d87b. PMID: 23340393
  33. Dickel H, Bauer A, Brehler R, et al. German S1 guideline: Contact dermatitis. J Dtsch Dermatol Ges. 2022 May;20(5):712-734. doi: 10.1111/ddg.14734. PMID: 35527339
  34. Ferri F. Contact dermatitis. ClinicalKey. https:\\www.clinicalkey.com. 01 Jan 2023.
  35. Klaschka F, Ring J. Systemically induced (hematogenous) contact eczema [Abstract]. Semin Dermatol. 1990 Sep;9(3):210-215. PMID: 2206921
  36. Levin C, Warshaw E. Protein contact dermatitis: allergens, pathogenesis, and management [Abstract]. Dermatitis. 2008 Sep;19(5):241-251. PMID: 18845114
  37. Litchman G, Nair PA, Atwater AR, et al. Contact dermatitis. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Sep.
  38. Patel K, Nixon R. Irritant contact dermatitis - a review. Curr Dermatol Rep. 2022 Apr;11(2):41-51. doi: 10.1007/s13671-021-00351-4. PMID: 35433115
  39. Schloemer JA, Zirwas MJ, Burkhart CG. Airborne contact dermatitis: Common causes in the USA. Int J Dermatol. 2015 Mar;54(3):271-274. doi: 10.1111/ijd.12692. PMID: 24981079
Editor's Recommendations
Special Reports