Patients w/ abnormal Pap smear are referred for colonoscopy to screen for presence of cervical cancer.
Colposcopic exam should include inspection of the transformation zone, definition of the extent of the lesion & biopsy of the most abnormal area for tissue diagnosis.
The earliest stages of cervical carcinoma are generally asymptomatic.
Watery vaginal discharge & postcoital bleeding or intermittent spotting may be present & are usually unrecognized by the patient.
Minimally invasive radical hysterectomy is associated with poorer survival than open surgery in patients with early-stage cervical cancer, data from two large US databases and a randomized trial have shown.
Endocervical sampling with a new fabric-based curette device reduces the number of “inadequate” specimens and hence, the need for repeat biopsies compared with conventional metal scraping, reveals a recent study.
Patients with locally advanced cervical cancer should not be routinely treated with neoadjuvant chemotherapy (NACT) followed by surgery as this approach does not improve disease-free survival (DFS) or overall survival (OS) vs standard chemoradiotherapy (CRT), according to results of a phase III trial.
Dr Ravichandran Nadarajah, a consultant at the Department of Obstetrics & Gynaecology, Singapore General Hospital, speaks to Roshini Claire Anthony on the importance of early diagnosis and prevention of cervical cancer.
The addition of bevacizumab to chemotherapy improved overall survival (OS) in women with metastatic, persistent, or recurrent cervical cancer, according to the final OS analysis of the Gynecologic Oncology Group (GOG) 240 trial, confirming the findings observed in the interim analysis.
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Pregnant women with inadequate knowledge on health are more likely to have undesirable maternal outcomes during delivery and adverse outcomes in their offspring than those who were well informed, according to a large cohort study presented at SMFM 2020 Annual Pregnancy Meeting.