Cataract is the presence of opacity in the crystalline lens of the eye. It causes painless, progressive blurring of vision.
It is the leading cause of blindness worldwide and the most prevalent ocular disease.
The initiating events that lead to loss of transparency of both the cortical and nuclear lens tissue is the oxidation of the membrane lipids, structural or enzymatic proteins or DNA by peroxidases or free radicals induced by UV light.
Children with uveitis commonly develop cataract, and the development of the eye disease is strongly associated with the extent of inflammation recurrences and ocular complications, according to a cohort study.
Paediatric patients with uveitis commonly develop cataract, and the risk of cataract development increases with the extent of inflammation recurrences and ocular complications, according to a cohort study.
More than two-thirds of adults with visually significant cataract are unaware of their condition, and half of those undiagnosed have bilateral visual impairment, results from the Singapore population-based SEED* study show.
The use of intraoperative wavefront aberrometry (IWA) in calculating intraocular lens (IOL) power during routine cataract surgery is not reliable due to its high rate of measurement failures and the large variations of the readings, a study has shown.
A new population-based study has reported that at least 66 percent of Singaporean adults have undiagnosed visually significant cataracts, and that a further half of this experience considerably reduced qualities of life as a result of bilateral visual impairment.
Patients undergoing chemotherapy for breast or haematological cancers could potentially reduce their risk of chemotherapy-related cardiotoxicity with the use of angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor antagonists (ARBs), or beta-blockers as primary prevention, according to a systematic review and meta-analysis presented at the recent EuroEcho 2019 conference.
Men who undergo flexible cystoscopy, particularly with a longer dwell time, may benefit from intraurethral lidocaine as it provides significant pain reduction, suggest the results of a meta-analysis. Evidence is lacking for other tested interventions.