Cataract is the presence of opacity in the crystalline lens of the eye. It causes painless, progressive blurring of vision.
It is the leading cause of blindness worldwide and the most prevalent ocular disease.
The initiating events that lead to loss of transparency of both the cortical and nuclear lens tissue is the oxidation of the membrane lipids, structural or enzymatic proteins or DNA by peroxidases or free radicals induced by UV light.
Paediatric patients with uveitis commonly develop cataract, and the risk of cataract development increases with the extent of inflammation recurrences and ocular complications, according to a cohort study.
More than two-thirds of adults with visually significant cataract are unaware of their condition, and half of those undiagnosed have bilateral visual impairment, results from the Singapore population-based SEED* study show.
The use of intraoperative wavefront aberrometry (IWA) in calculating intraocular lens (IOL) power during routine cataract surgery is not reliable due to its high rate of measurement failures and the large variations of the readings, a study has shown.
A new population-based study has reported that at least 66 percent of Singaporean adults have undiagnosed visually significant cataracts, and that a further half of this experience considerably reduced qualities of life as a result of bilateral visual impairment.
Based on the existing literature, there may be an association between the use of glucocorticoids and the subsequent development of cataract, a meta-analysis reports. However, because there isn’t enough evidence and adequate studies, this risk cannot be accurately determined for those with rheumatoid arthritis.
Persistent foetal vasculature (PFV) and its variants appear to be the most common ocular manifestation of unilateral congenital cataract in infants, but the prevalence of the significant cataract-related systemic disease is rather low, according to 5-year data from the Infant Aphakia Treatment Study (IATS).
The baseline inferior subfield retinal thickness may predict the frequency of treatment for diabetic macular oedema (DME) during the first year in eyes administered pro re nata (PRN) intravitreal ranibizumab (IVR) injections, a new study shows.