A total diet replacement programme produces greater weight loss among people with obesity as compared with support from a practice nurse, with the benefit persisting to at least 3 years, a study has found.
The gonadotropin-releasing hormone (GnRH) antagonist degarelix and the GnRH agonist leuprolide appear to be similar in terms of the rate of cardiovascular events in a cohort of patients with prostate cancer, according to the results of the PRONOUNCE trial.
The investigational oral antiviral pill molnupiravir significantly slashed the risk of hospitalization or death by half in nonhospitalized adults with mild-to-moderate COVID-19, according to interim data from the phase III MOVe-OUT trial.
Among patients with chronic coronary syndromes, those with higher serum uric acid (SUA) levels are more likely to have major adverse cardiovascular (CV) events (MACE) and worse related quality of life (QoL), as reported in a study.
Patients who receive sacubitril-valsartan after an acute myocardial infarction (MI) have a similar health status, as determined by EQ-5D visual analog scale (VAS) score, compared with those who receive ramipril, according to results of a prespecified analysis of the PARADISE-MI trial presented at HFSA 2021.
Bedside genotype testing for mutations in the CYP2C19 gene helps select a better P2Y12 inhibitor treatment strategy for patients with ST-segment elevation myocardial infarction (STEMI) and leads to better outcomes relative to conventional therapy, a recent study has found.
Some whole-diet interventions, such as fat-modified diets, appear to exert favourable effects on some lipid profile markers, glycaemic indices, and blood pressure among postmenopausal women, as reported in a review. However, the findings are inconclusive, given the large heterogeneity in diets, comparisons, and population characteristics across a limited number of studies.