Elevated troponin T levels at hospital admission may be a harbinger of adverse outcomes in COVID-19 but could help risk-stratify patients, according to a new study. Those with cardiovascular disease (CVD) are also more vulnerable than those without, bolstering the suspected link between.
Patients with atrial fibrillation (AF) enrolled in the prospective Global Anticoagulant Registry in the FIELD-AF (GARFIELD-AF) have been prescribed the recommended direct oral anticoagulant (DOAC) doses according to country-specific guidelines. However, use of nonrecommended doses persists and is associated with a higher risk of death, mostly of cardiovascular nature, reveals a study.
Shortness of breath, or dyspnoea after some exertion, can sometimes be associated with reduced fitness and ageing. However, GPs should not overlook the possibility that the symptom could be a warning sign of heart and lung diseases, experts caution.
Patients with COVID-19 who experience an ischaemic stroke may have worse outcomes, including greater stroke severity and mortality risk, than those without COVID-19, findings from the Global COVID-19 Stroke Registry showed.
The pupil of the eye may independently predict all‐cause mortality and readmission due to heart failure (HF), suggesting its prognostic predictive capability in patients with HF, a retrospective analysis has shown.
The use of aspirin alone following TAVI* significantly reduced bleeding vs aspirin plus clopidogrel in the POPular TAVI study. This benefit came without increasing thromboembolic events, effectively positioning aspirin as the better antithrombotic strategy after TAVI.
Monthly injections of the PCSK9* monoclonal antibody evolocumab effectively reduced plasma LDL-cholesterol (LDL-C), often referred to as the bad cholesterol, in teenagers with heterozygous familial hypercholesterolaemia (HeFH) already taking statins, with or without ezetimibe, the HAUSER-RCT has shown.
Inhaled treprostinil significantly improves exercise capacity in terms of 6-minute walking distance (6MWD) over 16 weeks compared with placebo in patients with pulmonary hypertension associated with interstitial lung disease (ILD), according to the INCREASE trial presented at ATS 2020.
In patients with chronic heart failure with reduced ejection fraction (HFrEF), empagliflozin reduced the risk of cardiovascular (CV) death or heart failure hospitalization (HHF) and decline in estimated glomerular filtration rate (eGFR), results of the EMPEROR-Reduced* trial showed.
Diabetes is a key risk factor for heart failure (HF), which is the leading cause of hospitalization in patients with or without diabetes. SGLT-2* inhibitors (SGLT-2is) have been shown to reduce the risk of hospitalization for HF (HHF) regardless of the presence or absence of diabetes.
The substitution of isoleucine to leucine at amino acid 97 (I97L) in the core region of the hepatitis B virus (HBV) seems to reduce its potency, decreasing the efficiency of both infection and the synthesis of the virus’ covalently closed circular (ccc) DNA, reports a new study presented at The Liver Meeting Digital Experience by the American Association for the Study of Liver Diseases (AASLD 2020).