The 30-day mortality rates among patients undergoing transcatheter aortic valve replacement (TAVR) have decreased by more than half over the last decade, with significant differences between genders, a CENTER* collaboration analysis has shown.
In older adults with systolic hypertension, targeting a 24-hour ambulatory systolic blood pressure (BP) of ≤130 vs ≤145 mm Hg does not appear to be beneficial in terms of mobility outcomes during a 3-year period, although it yields a favourable effect on subcortical white matter disease, according to data from the INFINITY trial.
A once-weekly exenatide regimen is safe and well tolerated in diabetic patients with or without heart failure (HF), although its beneficial effects on all-cause death and first HF hospitalization appear to be weakened in those without HF at baseline, according to the results of the EXSCEL* trial.
Iron supplementation results in reduced heart failure hospitalization, enhanced cardiac function and exercise capacity, better quality of life, and lower serum levels of pro-B-type natriuretic peptide (NT-proBNP) and C-reactive protein (CRP) in patients with heart failure, according to a meta-analysis.
The antithrombotic potency of ticagrelor alone on ex vivo whole blood thrombogenicity does not differ from that of ticagrelor plus aspirin in high-risk patients who have undergone percutaneous coronary intervention (PCI), according to the thrombogenicity substudy of the TWILIGHT* trial.
In patients with high-bleeding risk, undergoing PCI* with a polymer-based drug-eluting stent (DES) was noninferior to a polymer-free drug-coated stent (DCS) when followed by a 1-month dual antiplatelet therapy (DAPT), according to the Onyx ONE** trial presented at TCT 2019.
While a diagnosis of cancer is often met with concern and devastation, the same is barely true for heart failure. However, the mortality rate for those suffering from heart failure is worse than some common cancers, such as prostate and breast cancers.
In low-risk patients with severe aortic stenosis (AS), those treated with transcatheter aortic valve replacement (TAVR) had a significantly better disease-specific health status at 1 year compared with those who received surgical aortic valve replacement (SAVR), according to the PARTNER 3* trial presented at TCT 2019.
Low total cholesterol levels appear to carry increased major adverse cardiovascular events (MACE) hazard in older men without ischaemic heart disease (IHD) and not receiving statin therapy but not to those on statins, according to data from the CHAMP (Concord Health and Ageing in Men Project) cohort.
Using blunt needles to administer local anaesthesia in upper blepharoplasty has a lower risk of haemorrhage and need for interventional pain procedures compared with sharp needles, a new randomized clinical trial has found.
In patients with acute ST-segment elevation myocardial infarction (ASTEMI), the risk of new-onset atrial fibrillation (NOAF) appears to be linked with plasma levels of low-density lipoprotein cholesterol (LDL-C) and total cholesterol (TC), a recent China study has found.