In patients with heart failure with reduced ejection fraction (HFrEF) receiving angiotensin-converting-enzyme (ACE) inhibitors, high dosing confers benefits for the risk of death or hospitalization that are similar to that obtained with lower dosing, according to a systematic review and meta-analysis.
Individuals who reported a long nap duration of 60 minutes/day had a higher risk of cardiovascular disease (CVD) and all-cause mortality than those who did not take any daytime naps, according to a study presented at ESC 2020.
In patients with heart failure with preserved ejection fraction (HFpEF), angiotensin-neprilysin inhibition with sacubitril/valsartan confers better renoprotection than valsartan alone, reducing the risk of adverse renal events and the speed of decline in estimated glomerular filtration rate (eGFR), a study has found.
Patients hospitalized with mild-to-moderate COVID-19 who are on angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) for hypertension should continue these medications, according to primary results of the BRACE CORONA trial presented at ESC 2020.
Several factors, including body mass index (BMI), diabetes mellitus, and age, are associated with the risk of progression from prehypertension to hypertension among middle-aged and elderly adults, according to a 12-year Korean cohort study.
Early initiation of rhythm-control therapy led to a significantly reduced risk of major adverse cardiovascular (CV) outcomes compared with usual care (typically rate control) in patients with newly diagnosed atrial fibrillation (AF) at risk of stroke, reveals the EAST-AFNET 4* trial presented at ESC 2020.
More than two-thirds of Asian patients with ischaemic diabetic heel ulcers survived without requiring an amputation at 1 year following lower limb revascularization surgery — a rate better than previously reported in the literature, according to a local study.
A prasugrel de-escalation strategy significantly reduced the risk of NACE* and bleeding events in patients with ACS** after PCI*** compared with the conventional strategy, results of the HOST-REDUCE-POLYTECH-ACS# trial have shown.
Patients with multivessel coronary artery disease (CAD) and diabetes treated with coronary artery bypass grafting (CABG) have improved long-term mortality and freedom from major cardiovascular and cerebrovascular events (MACCEs) compared to those treated with percutaneous coronary intervention (PCI), according to a study.
The combination therapy comprising carfilzomib, cyclophosphamide and dexamethasone (KCd) is effective, with a tolerable safety profile, in an Asian cohort with high-risk multiple myeloma (MM) — thus providing a more economical alternative as a potential upfront regimen in resource-limited settings, according to leading experts during a myeloma education webinar.
Extremes of sleep duration (≤5 or ≥10 hours/day), which is a known mortality risk factor in the general population, may increase absolute mortality in adults with type 2 diabetes (T2D), a prospective study has shown.