Complete revascularization has been shown to be superior to culprit-lesion-only percutaneous coronary intervention (PCI) in reducing major cardiovascular (CV) events, according to results of the COMPLETE trial reported at the European Society of Cardiology (ESC) Congress 2019 and World Congress of Cardiology (WCC) 2019.
Radiation heart dosimetric parameters appear to exert neutral effect on overall survival (OS) in nonsmall cell lung cancer patients undergoing postoperative thoracic radiotherapy (PORT), according to a recent Singapore study.
More intensive LDL-lowering by adding ezetimibe to simvastatin in elderly individuals aged ≥75 years significantly reduced recurrent cardiovascular (CV) events without raising safety issues compared with simvastatin alone, a secondary analysis of the IMPROVE-IT* has shown.
Rivaroxaban monotherapy offers noninferior efficacy and superior safety compared with its combination with an antiplatelet agent in the treatment of patients with atrial fibrillation (AF) and stable coronary artery disease (CAD), results of the Japanese AFIRE trial have shown.
Use of sodium glucose cotransporter 2 (SGLT2), as compared with dipeptidyl peptidase 4 (DPP4), inhibitors appears to reduce the risk of heart failure and any-cause death without major cardiovascular events in the primary intention-to-treat analysis, according to a study.
DOACs* were better than warfarin in terms of efficacy and safety for stroke prevention in an Asian population with atrial fibrillation (AF) and liver disease, including patients with significant active liver disease who were usually excluded from pivotal clinical trials, suggests a study based on the Korean national database.
The angiotensin receptor-neprilysin inhibitor (ARNI) sacubitril/valsartan has demonstrated a modest effect vs valsartan alone on hospitalization and death in patients with heart failure with preserved ejection fraction (HFpEF), with results suggesting a greater benefit in women and patients with borderline low left ventricular EF (LVEF).
The use of songs as mental metronomes for cardiopulmonary resuscitation (CPR) is accepted by contemporary guidelines, and the National Day song ‘Count on me Singapore’ (COMS) is not an exception, with a recent study finding it noninferior to standard ‘one-and-two-and-three’ counting (standard CPR) in terms of participants delivering a guideline-compliant rate of chest compression.
An observational study has found that high and increasing blood pressure (BP) from early adulthood into midlife seems to be associated with increased white matter hyperintensity volume (WMHV) and smaller brain volumes at 69 to 71 years of age.
Use of aspirin in the primary prevention of cardiovascular disease (CVD) in patients with no prior CVD history yields protection against the risks of acute myocardial infarction (AMI) and ischaemic stroke, but at the expense of an increase of similar magnitude in the incidence of major bleeding, according to the results of a recent meta-analysis presented at the European Society of Cardiology (ESC) Congress 2019 in Paris, France.
A comprehensive model of care delivered by nonphysician health workers (NPHWs), involving primary care physicians and families that was informed by local context, substantially improved blood pressure (BP) control and cardiovascular disease (CVD) risk, according to results of the HOPE 4 trial reported at the European Society of Cardiology (ESC) Congress 2019 and World Congress of Cardiology (WCC) 2019.