Eating avocado does not appear to have a significant effect on serum total cholesterol (TC), low-density lipoprotein (LDL) cholesterol and triglyceride (TG) concentrations, but it has increased serum high-density lipoprotein (HDL) cholesterol concentrations, with significant heterogeneity, reports a study.
Concomitant use of direct oral anticoagulants (DOACs) and amiodarone, a dual P-glycoprotein (p-gp)/ cytochrome p-450 (CYP3A4) inhibitor, appears to have no influence on the efficacy and safety outcomes in patients with atrial fibrillation, suggest the results of a recent meta-analysis.
Treatment with danegaptide does not improve myocardial salvage in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention, according to the results of a phase II study.
Treatment with mineralocorticoid antagonists (MRAs) appears to be useful in lowering blood pressure (BP) in already treated hypertensive patients who did not reach target BP values, according to the results of a meta-analysis.
In an analysis of the Systolic Pressure Intervention Trial (SPRINT), intensive treatment of hypertension has been shown to provide more harm than benefit to patients with lower baseline cardiovascular disease (CVD) risk and more benefit to those with higher risk.
Patients with permanent atrial fibrillation (AF) are at greater risk of developing heart failure, a study has found. Predictors of AF progression include AF duration, diabetes mellitus, heart failure, hyperthyroidism, sinus rhythm, cardioversion and valvular heart disease.
Impaired endothelial-dependent microvascular reactivity appears to be predictive of albuminuria progression in Asian patients with type 2 diabetes (T2D) who have normal urine albumin levels at baseline, but not in those with microalbuminuria, a prospective longitudinal cohort study suggests.
Varenicline, while effective for smoking cessation, appears to significantly elevate the risk of cardiovascular hospitalization and emergency department visits, particularly for new users, a recent study shows.
In children, a short duration of sleep appears to be a significant risk factor for elevated cardiometabolic risk, suggesting that parents need to be mindful of their children’s sleep hygiene, a recent Spanish study has shown.
Physicians’ practice patterns in managing hypertension, and their awareness of blood pressure variability, were reported in a recent study in Singapore. We discussed some of the clinical practice gaps identified by this study with author, A/Prof. Teo Boon Wee.