Top Medical News
17 hours ago
The risk of fatal and nonfatal cardiovascular disease (CVD) is elevated in individuals with histories of gallstone disease (GD), a recent study has found.
21 hours ago
Long-term use of benzodiazepines is independently associated with lower diastolic and systolic blood pressure in ambulatory blood pressure monitoring (ABPM) among older but not younger patients, a study has found.
Stephen Padilla, Yesterday
Frank’s sign, a diagonal crease in the earlobe that starts from the tragus to the edge of the auricle in an angle of 45° in varying depths, is a risk factor for ischaemic cerebrovascular events, a recent study has found. Its prevalence is high among patients with classical cardiovascular (CV) predictors.
Higher home blood pressure (BP) predicts the incidence of stroke even among patients with impaired physical function, a recent study suggests.
Pearl Toh, 2 days ago
An initial strategy of 1-year romosozumab followed by alendronate is superior over alendronate alone in reducing new vertebral fractures in postmenopausal women with osteoporosis at high risk for fracture, according to the ARCH* study.
2 days ago
Patients with renal artery stenosis (RAS) are more likely to experience left ventricular hypertrophy (LVH) than their counterparts with essential hypertension, according to a recent study. In addition, renal artery revascularization is beneficial on LV structure, as shown by a substantial reduction in LV mass index.
3 days ago
High concentrations of circulating chemerin are associated with elevated risks of heart failure (HF), a recent study suggests. On the other hand, omentin-1 levels were not correlated with HF risk.
Special Reports
08 Nov 2017
Available in Europe since 1978, trimetazidine was launched in Malaysia in 1986 as VASTAREL® 20, with the first box of this medication sold in 1987. At that time, this agent was available as three times daily dosing; this was soon followed by the modified-release formulation, ie, VASTAREL® MR®, launched in 2005 to simplify the dosing regimen. By 2007, VASTAREL® MR® had become widely available in public hospitals throughout Malaysia.The efficacy of trimetazidine in coronary artery disease (CAD) is well established – it is a well-tolerated anti-ischaemic agent with no effect on blood pressure or heart rate. It is also recommended by Malaysian and international guidelines for symptomatic relief of angina. In conjunction with the 30th anniversary of VASTAREL®, renowned local and international opinion leaders gathered at a Servier symposium, chaired by Dr Jeyamalar Rajadurai, to reflect on the evolution of CAD management and the contemporary role of trimetazidine.
Dr. Yeo Khung Keong, Dr. Wiwun Tungsubutra, Prof. Peter Collins, 31 Aug 2017
Agents such as beta-blockers and calcium antagonists have been the cornerstone of treatment for stable angina for some time. However, new options are emerging for patients who remain inadequately controlled on conventional therapies. At a recent Menarini-sponsored symposium held during the APSC Congress 2017 in Singapore, three experts discussed the current treatment landscape, as well as changing paradigms and new effective options for patients with symptomatic angina.
23 Aug 2017
Results from a survey presented at the 2017 Asia Pacific Society of Cardiology Congress indicate that 98% of respondents involved in managing patients with hypertension in Singapore recommend home blood pressure monitoring (HBPM) to patients with hypertension. However, a number of barriers remain to the effective use of out-of-office blood pressure (BP) monitoring.
Prof. Peter Collins, Prof. Giuseppe Mancia, Prof. Carolyn Lam, Dr. Choo Gim Hooi, 12 Jul 2017
Coronary artery disease (CAD) is the leading cause of death worldwide and is expected to remain so for the foreseeable future due to both the ageing population and the increasing prevalence of risk factors such as hypertension, dyslipidaemia, and diabetes. CAD is also the primary risk factor in the development of heart failure (HF). At the 2nd Asia Pacific CardioConnect Meeting in Hong Kong sponsored by Menarini, a group of international and regional experts discussed current strategies for managing stable CAD and HF and highlighted areas where patient outcomes may be improved.
25 May 2017
At a recent lunch symposium during the 14th Annual Scientific Meeting of the Malaysian Society of Hypertension, Dr Chow Yok Wai spoke on the importance of patient adherence in the management of hypertension, highlighting the role of combination therapy in improving treatment outcomes.
24 Apr 2017
Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used to treat pain and inflammation in patients with arthritis, but the vascular effects of some NSAIDs have cast doubt on whether they can be used in patients at risk for cardiovascular (CV) disease. At the American Heart Association’s Scientific Sessions 2016 held recently in New Orleans, Louisiana, US, Professor Steven Nissen of the Cleveland Clinic in Cleveland, Ohio, US, presented latest data from the PRECISION (Prospective Randomized Evaluation of Celecoxib Integrated Safety vs Ibuprofen or Naproxen) trial that evaluated the CV risk and safety profile of the selective cyclooxygenase-2 (COX-2) inhibitor celecoxib vs nonselective NSAIDs.
16 Mar 2017
Recently, Dr Peter Lin of the Canadian Heart Research Centre spoke on treatment strategies in the management of dyslipidaemia and T2DM at an AstraZeneca-sponsored continuing medical education event. Highlights of his presentations are summarized below.
Conference Reports
Pearl Toh, 16 Nov 2017
Using bioabsorbable polymer drug-eluting stents (DES) with a shorter duration of double antiplatelet therapy (DAPT) in elderly patients undergoing percutaneous coronary intervention (PCI) leads to fewer adverse events than bare-metal stents (BMS) without increasing bleeding risk, according to the SENIOR* trial presented at TCT 2017 Congress.
Pearl Toh, 14 Nov 2017
Performing percutaneous coronary intervention (PCI) on culprit lesion only, rather than a multivessel PCI, reduces the 30-day composite risk of death or severe renal failure in patients with acute myocardial infarction (MI) complicated by cardiogenic shock and multivessel disease, according to the CULPRIT-SHOCK* study presented at the TCT 2017 Congress held in Denver, Colorado, US.
Elaine Soliven, 06 Nov 2017
Greater waist circumference (WC) may be a useful predictor for elevated blood pressure (BP) in children and adolescents, according to a study presented at the 13th Asian-Pacific Congress of Hypertension held in Singapore.
Pearl Toh, 31 Oct 2017
Nationwide collaborative efforts are necessary to highlight the importance of cardiac rehabilitation (CR), said Dr Yeo Tee Joo, Consultant Cardiologist at the National University Heart Centre, Singapore, during the recent SPCRS 2017, calling for efforts to increase awareness of CR benefits, utilization of technology, and formation of support groups for patients.
Roshini Claire Anthony, 30 Oct 2017

Elderly patients with angina who have undergone percutaneous coronary intervention (PCI) are less likely to correctly manage recurring symptoms than younger patients, thus more effective methods of encouraging proper management in this group of patients is required, according to a poster presented at the recent Singapore Prevention & Cardiac Rehabilitation Symposium 2017 (SPCRS 2017).

Pearl Toh, 30 Oct 2017
A multidisciplinary inpatient cardiac rehabilitation programme (CRP) helps reduce risk factors for coronary heart disease (CHD) and improves proper prescription of evidence-based medication as well as patient's knowledge about the disease, according to a study presented at SPCRS 2017.
Stephen Padilla, 30 Oct 2017
Discharge instruction has led to improvements in knowledge, compliance and comprehension on medication among adult cardiac service patients, according to a study presented at the Singapore Prevention & Cardiac Rehabilitation Symposium (SPCRS) 2017. Furthermore, it appears that discharge planning confers a clearer and more comprehensive medication instruction.
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