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Cardiology
Top Medical News
Intensive cholesterol-lowering therapy yields substantial reductions in the risk of atherosclerotic cardiovascular disease (ASCVD) over a 30-year period. This can be achieved if therapy is initiated in individuals in their 40s and 50s with nonhigh-density lipoprotein cholesterol (non-HDL-C) levels at least 160 mg/dL, according to a team of researchers.
Individuals at high risk for influenza who receive an influenza vaccination may have a reduced risk of cardiovascular (CV) events, according to a retrospective study presented at BCVS* 2020.
In this final issue of our series, join us as we
look into the upcoming results of the pivotal EMPEROR trials, which will
investigate the use of empagliflozin in patients with either preserved or
reduced ejection fraction heart failure, with or without type 2 diabetes.
Understand why heart failure has such a high clinical burden, and the great
unmet need in providing solutions for it.
Circulating interleukin (IL)-6 correlates with worse baseline haemodynamics and may be indicative of clinical worsening in kids with pulmonary arterial hypertension, a recent study has shown.
Patients with erectile dysfunction (ED) have elevated values of atherogenic index of plasma (AIP), a recent study has found.
Women who develop diabetes show less favourable changes in cardiovascular disease (CVD) risk factors, such that blood pressure and lipid levels deteriorate rapidly compared with their male counterparts, a study has found.
Valve-in-valve (VIV) transcatheter aortic valve replacement (TAVR) leads to better short-term outcomes than redo surgical aortic valve replacement (SAVR) in patients treated for aortic bioprosthesis failure, a recent study has shown. During long-term follow-up, no difference is seen in major cardiovascular outcomes between the two treatment arms.
Special Reports
In this final issue of our series, join us as we
look into the upcoming results of the pivotal EMPEROR trials, which will
investigate the use of empagliflozin in patients with either preserved or
reduced ejection fraction heart failure, with or without type 2 diabetes.
Understand why heart failure has such a high clinical burden, and the great
unmet need in providing solutions for it.
In this fourth issue,
join us as we discover the unique biology Asians have with respect to diabetes.
Take a closer look at trials evaluating whether empagliflozin’s cardiovascular
and renal benefits – as analysed in Asians – are consistent with the overall
trial population, and how it addresses unmet needs.
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Hyperkalaemia (HK) occurrence and recurrence are frequent in advanced CKD*, creating a perfect storm for cardiovascular events and death, says Professor Juan-Jesus Carrero from the Karolinska Institute, Solna, Sweden, at ERA-EDTA 2020. Given these risks, acutely elevated potassium (K+) should merit clinical attention.
Rosuvastatin calcium 5 mg, 10 mg and 20 mg FC tab
In this third issue we take
a look at how empagliflozin made a bold impact on clinical guidelines across
multiple specialties. We will explore how existing treatment recommendations
were altered, and summarise the current guidelines and future perspectives of
empagliflozin’s use.
This second issue revisits the impact EMPA-REG OUTCOME had on clinical
practice and helps readers discover how it gives life back to patients
through its cardiovascular indication. Learn how it was approved and the
possible
mechanisms for its cardiovascular benefits.
Dropping aspirin after 3 months of dual therapy with ticagrelor reduced bleeding in patients with diabetes who have undergone PCI* vs taking both agents for 1 year, the TWILIGHT-DM** study has shown, consistent with benefits seen in TWILIGHT for other high-risk patients.
Conference Reports
Thrombotic complications are rife among in-hospital patients with COVID-19, with patients in the ICU particularly at risk compared with those in the general wards, a study released at the ISTH 2020 Meeting has shown.
Having no restriction on oral food intake before cardiac catheterization appears to be as safe as the current standard fasting strategy, according to the CHOW NOW randomized trial presented during the SCAI 2020 Virtual Scientific Sessions.
The prescription omega-3 fatty acid icosapent ethyl significantly reduces the need for revascularization in patients with elevated triglycerides who were already on statins and were at increased cardiovascular (CV) risk, reveals the latest data from the REDUCE-IT REVASC analysis presented during the SCAI* 2020 Meeting.
Dropping aspirin after 3 months of dual therapy with ticagrelor reduced bleeding in patients with diabetes who have undergone PCI* vs taking both agents for 1 year, the TWILIGHT-DM** study has shown, consistent with benefits seen in TWILIGHT for other high-risk patients.
Among patients undergoing complex percutaneous coronary intervention (PCI) who completed 3 months of dual antiplatelet therapy (DAPT) comprising aspirin and the potent P2Y12-receptor inhibitor ticagrelor, aspirin withdrawal led to fewer bleeding episodes without increasing the risk of ischaemic events compared with continued DAPT, according to data from the TWILIGHT-COMPLEX* subanalysis presented at ACC.20/WCC Virtual.
Taking ticagrelor alone — and dropping aspirin — after 3 months of DAPT* post-PCI** significantly reduced bleeding events without increasing the risk of ischaemic adverse events compared with continuing a DAPT of ticagrelor plus aspirin, the TICO*** trial has shown.
Patients with cancer who develop venous thromboembolism (VTE) could reduce their risk of VTE recurrence with the direct oral anticoagulant (DOAC) apixaban, which demonstrated noninferiority to subcutaneous dalteparin in the Caravaggio* trial.
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