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Future TTR in atrial fibrillation patients on VKA

Yesterday

Nearly half of atrial fibrillation (AF) patients on vitamin K antagonist (VKA) with prior time in therapeutic range (TTR) ≥70 percent had TTR <70 percent during the following year, reports a recent study. Additionally, there is limited long-term prognostic value for prior TTR ≥70 percent.

White-coat, masked hypertension tied to risk of new-onset metabolic syndrome

Yesterday

Isolated or combined blood pressure (BP) elevations identified by office or ambulatory measurements are associated with a greater risk of new-onset metabolic syndrome (MetS), suggests a recent study. On the other hand, only white-coat hypertension (WCH) is linked to an increased risk of incident MetS whenever BP phenotypes are identified by office or home measurement.

Prasugrel contraindication in ACS patients tied to worse in-hospital, postdischarge outcomes

2 days ago

Acute coronary syndrome (ACS) patients with prasugrel contraindications tend to have worse in-hospital and postdischarge prognosis, according to a recent study, which reports that ticagrelor may be an effective alternative.

Lifestyle changes cut need for BP meds

Pearl Toh, 2 days ago

Lifestyle interventions incorporating diet and exercise slash the need for antihypertensive medications by more than half among overweight or obese adults with high blood pressure (BP), according to a secondary analysis of the ENCORE trial presented at the Joint Hypertension 2018 Scientific Sessions.

Epicardial LAAE lowers blood pressure in hypertensive patients with AF

2 days ago

Epicardial relative to endocardial left atrial appendage exclusion (LAAE) significantly reduces systolic blood pressure (SBP) in patients with atrial fibrillation (AF) and hypertension both at 3 and 12 months, according to a study.

Exposure to fluoroquinolone linked to risk of aortic aneurysm, dissection

2 days ago

A significant association exists between fluoroquinolone exposure and aortic aneurysm and dissection (AA/AD), suggests a recent study. Duration of fluoroquinolone use and length of the hazard period modify this risk.

Lessons from the TREAT trial: Ticagrelor is as safe as clopidogrel for STEMI patients treated with fibrinolysis

01 Sep 2018

Ischaemic heart disease was the principal cause of death in Malaysia in 2016, and ST-segment elevation myocardial infarction (STEMI) is noted as the deadliest clinical presentation of Acute Coronary Syndrome. At the National Heart Association of Malaysia’s 2018 Annual Scientific Meeting, Professor Dr Wan Azman Wan Ahmad shared his insights into the management of STEMI in Malaysia, highlighting the implications of the recent TREAT trial.

Redefining diabetes management: Combining glycaemic control with cardiovascular protection to deliver better patient outcomes

31 May 2018

At the recent ‘Reinforced for the Glycaemic Challenge’ symposium held at Shangri-la Hotel, Kuala Lumpur, Associate Professor Dr Alexander Tan, Professor Dr Chee Kok Han and Dr Chan Siew Pheng shared their insights into the importance of achieving glycaemic control in patients with type 2 diabetes mellitus (T2DM), while simultaneously providing them with cardiovascular protection.

MIMS Cardiology Supplement April 2018

30 Apr 2018

In this issue of MIMS Cardiology Supplement, we bring you clinical updates related to combating hypercholesterolaemia, highlighting the role of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors in lowering low-density lipoprotein-cholesterol levels.

HOPE Asia Network consensus recommendations on home blood pressure monitoring

12 Apr 2018

Home blood pressure monitoring (HBPM) is increasingly being recognized as an accurate adjunct to clinic blood pressure measurement for the diagnosis and management of hypertension. We discussed the HOPE Asia Network’s recently published consensus recommendations on HBPM with lead author, Prof. Sungha Park.

Click here to view the interview video with one of the authors - Professor Sungha Park

Optimizing the role of home blood pressure monitoring: The Asia BP@Home study

12 Apr 2018

In an effort to better understand hypertension subtypes – including morning and white-coat hypertension – in Asian patients, the HOPE Asia Network has initiated the Asia BP@Home study across 12 countries and regions. We discussed the study’s design and objectives with lead investigator, Prof. Kazuomi Kario.

Click here to view the interview video with lead investigator - Professor Kazuomi Kario

Non–high-density lipoprotein cholesterol: A better marker for cardiovascular outcomes?

01 Mar 2018

At a cardiology conference held in Hilton Kuala Lumpur, senior consultant cardiologist Dato’ Sri Dr Azhari Rosman spoke on the importance of non–high-density lipoprotein cholesterol (non–HDL-C) and combination therapy as a novel approach in the management of atherogenic dyslipidemia (AD).

Very early invasive care not superior to standard approach in NSTE-ACS

Christina Lau, 10 Sep 2018

Very early invasive coronary angiography within 12 hours does not significantly improve long-term outcomes of patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS) compared with the standard strategy of evaluation within 48–72 hours, according to results of the VERDICT trial reported at the European Society of Cardiology (ESC) Congress 2018.

Switch to oral antibiotics effective and safe in stable left-sided infective endocarditis

Christina Lau, 07 Sep 2018

In patients with left-sided infective endocarditis in stable condition, switching to oral antibiotics is as effective and safe as continued treatment with intravenous (IV) antibiotics, according to results of the POET trial reported at the European Society of Cardiology (ESC) Congress 2018.

Extended rivaroxaban cuts post-discharge VTE, but not mortality, in medically ill patients

Christina Lau, 07 Sep 2018

Treatment with rivaroxaban for 45 days after hospital discharge reduces symptomatic venous thromboembolism (VTE), but not VTE-related mortality, in medically ill patients, results of the MARINER trial have shown.

Extended ticagrelor monotherapy after PCI not superior to standard DAPT

Christina Lau, 06 Sep 2018

Extending ticagrelor therapy to 2 years with aspirin given for only 1 month after percutaneous coronary intervention (PCI) is not superior to standard treatment, according to results of the GLOBAL LEADERS trial reported at the European Society of Cardiology (ESC) Congress 2018.

High-sensitivity troponin assay does not improve outcomes for MI patients

Dr. Joseph Delano Fule Robles, 04 Sep 2018

The use of high-sensitivity cardiac troponin assays was not associated with a lower subsequent incidence of myocardial infarction (MI) or cardiovascular death at 1 year, according to results of the High-STEACS trial reported at the European Society of Cardiology (ESC) Congress 2018.

New ESC/ESH hypertension guidelines recommend 2-in-1 combo pill as initial therapy

Christina Lau, 03 Sep 2018

The new 2018 European Society of Cardiology (ESC)/European Society of Hypertension (ESH) guidelines for the management of arterial hypertension recommend starting treatment for most patients with a two-in-one pill containing an angiotensin-converting enzyme inhibitor (ACEI) or angiotensin receptor blocker (ARB) in combination with a calcium channel blocker (CCB) or diuretic.

Percutaneous mitral-valve repair appears futile

Jackey Suen, 03 Sep 2018

Percutaneous mitral-valve repair with MitraClip failed to improve clinical outcomes in chronic heart failure (HF) patients with severe secondary mitral regurgitation, according to the MITRA-FR study presented at the European Society of Cardiology (ESC) Congress 2018.

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