Top Medical News
Tristan Manalac, 7 hours ago
Among males but not females, the risk of new-onset peripheral vestibular disorder (PVD) is strongly associated with a smoking history of ≥30 pack-years, a new retrospective cohort study has shown.
Elvira Manzano, Yesterday
There are no advantages to liberal use of red blood cell (RBC) transfusion over restrictive use in moderate to high-risk patients undergoing cardiac surgery, the multicentre randomized noninferiority TRICS-III* trial has shown.
Pearl Toh, Yesterday
A higher dose of pitavastatin can benefit Japanese patients with stable coronary artery disease (CAD) compared with a low-dose pitavastatin, even though cardiovascular (CV) event incidence is known to be lower in Asian than Western patients, according to the REAL-CAD study presented at the AHA Scientific Sessions 2017.
Jairia Dela Cruz, Yesterday
Higher levels of both recreational and nonrecreational physical activity can cut the risk of death and cardiovascular disease (CVD) in individuals from countries of all income levels, according to data from the Prospective Urban Rural Epidemiologic (PURE) study.
Roshini Claire Anthony, 2 days ago

A combination of ticagrelor and aspirin improved the saphenous vein graft (SVG) patency rate 12 months after coronary artery bypass grafting (CABG) compared with aspirin alone, according to results of the DACAB* trial from China.

2 days ago
Combining the DASH (Dietary Approaches to Stop Hypertension) diet with low sodium intake reduces systolic blood pressure (SBP) in individuals with pre- and stage 1 hypertension, with progressively higher reductions at greater levels of baseline SBP, a recent study has shown.
Stephen Padilla, 2 days ago
The use of direct oral anticoagulants (DOACs) lowers the risk of stroke and all-cause mortality in patients with atrial fibrillation (AF), suggests a recent study, adding that DOACs are safer than warfarin in regard to major and intracranial bleeding when used at doses to maintain an international normalized ratio (INR) of 2.0 to 3.0.
Special Reports
08 Nov 2017
Available in Europe since 1978, trimetazidine was launched in Malaysia in 1986 as VASTAREL® 20, with the first box of this medication sold in 1987. At that time, this agent was available as three times daily dosing; this was soon followed by the modified-release formulation, ie, VASTAREL® MR®, launched in 2005 to simplify the dosing regimen. By 2007, VASTAREL® MR® had become widely available in public hospitals throughout Malaysia.The efficacy of trimetazidine in coronary artery disease (CAD) is well established – it is a well-tolerated anti-ischaemic agent with no effect on blood pressure or heart rate. It is also recommended by Malaysian and international guidelines for symptomatic relief of angina. In conjunction with the 30th anniversary of VASTAREL®, renowned local and international opinion leaders gathered at a Servier symposium, chaired by Dr Jeyamalar Rajadurai, to reflect on the evolution of CAD management and the contemporary role of trimetazidine.
Dr. Yeo Khung Keong, Dr. Wiwun Tungsubutra, Prof. Peter Collins, 31 Aug 2017
Agents such as beta-blockers and calcium antagonists have been the cornerstone of treatment for stable angina for some time. However, new options are emerging for patients who remain inadequately controlled on conventional therapies. At a recent Menarini-sponsored symposium held during the APSC Congress 2017 in Singapore, three experts discussed the current treatment landscape, as well as changing paradigms and new effective options for patients with symptomatic angina.
23 Aug 2017
Results from a survey presented at the 2017 Asia Pacific Society of Cardiology Congress indicate that 98% of respondents involved in managing patients with hypertension in Singapore recommend home blood pressure monitoring (HBPM) to patients with hypertension. However, a number of barriers remain to the effective use of out-of-office blood pressure (BP) monitoring.
Prof. Peter Collins, Prof. Giuseppe Mancia, Prof. Carolyn Lam, Dr. Choo Gim Hooi, 12 Jul 2017
Coronary artery disease (CAD) is the leading cause of death worldwide and is expected to remain so for the foreseeable future due to both the ageing population and the increasing prevalence of risk factors such as hypertension, dyslipidaemia, and diabetes. CAD is also the primary risk factor in the development of heart failure (HF). At the 2nd Asia Pacific CardioConnect Meeting in Hong Kong sponsored by Menarini, a group of international and regional experts discussed current strategies for managing stable CAD and HF and highlighted areas where patient outcomes may be improved.
25 May 2017
At a recent lunch symposium during the 14th Annual Scientific Meeting of the Malaysian Society of Hypertension, Dr Chow Yok Wai spoke on the importance of patient adherence in the management of hypertension, highlighting the role of combination therapy in improving treatment outcomes.
24 Apr 2017
Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used to treat pain and inflammation in patients with arthritis, but the vascular effects of some NSAIDs have cast doubt on whether they can be used in patients at risk for cardiovascular (CV) disease. At the American Heart Association’s Scientific Sessions 2016 held recently in New Orleans, Louisiana, US, Professor Steven Nissen of the Cleveland Clinic in Cleveland, Ohio, US, presented latest data from the PRECISION (Prospective Randomized Evaluation of Celecoxib Integrated Safety vs Ibuprofen or Naproxen) trial that evaluated the CV risk and safety profile of the selective cyclooxygenase-2 (COX-2) inhibitor celecoxib vs nonselective NSAIDs.
16 Mar 2017
Recently, Dr Peter Lin of the Canadian Heart Research Centre spoke on treatment strategies in the management of dyslipidaemia and T2DM at an AstraZeneca-sponsored continuing medical education event. Highlights of his presentations are summarized below.
Conference Reports
Elvira Manzano, 12 Dec 2017
There are no advantages to liberal use of red blood cell (RBC) transfusion over restrictive use in moderate to high-risk patients undergoing cardiac surgery, the multicentre randomized noninferiority TRICS-III* trial has shown.
Pearl Toh, 12 Dec 2017
A higher dose of pitavastatin can benefit Japanese patients with stable coronary artery disease (CAD) compared with a low-dose pitavastatin, even though cardiovascular (CV) event incidence is known to be lower in Asian than Western patients, according to the REAL-CAD study presented at the AHA Scientific Sessions 2017.
Roshini Claire Anthony, 11 Dec 2017

A combination of ticagrelor and aspirin improved the saphenous vein graft (SVG) patency rate 12 months after coronary artery bypass grafting (CABG) compared with aspirin alone, according to results of the DACAB* trial from China.

Roshini Claire Anthony, 08 Dec 2017

The incidence of cardiovascular events in the first year following a primary percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI) is comparable between patients given prasugrel and ticagrelor post-surgery, according to results of the PRAGUE-18* trial presented at AHA 2017.

Pearl Toh, 05 Dec 2017
Extreme fluctuations in systolic blood pressure (SBP) between doctor visits for an extended period of time was associated with an increased risk of death from any cause than those with less extreme variability in BP, suggests a study presented at the AHA Scientific Sessions 2017.
Roshini Claire Anthony, 01 Dec 2017

The incidence of clinically significant hematoma is similar in individuals with atrial fibrillation undergoing pacemaker or defibrillator surgery regardless of whether their direct oral anticoagulants (DOACs) are continued or interrupted perioperatively, results of the BRUISE CONTROL-2* trial show.

Roshini Claire Anthony, 29 Nov 2017

Gastric bypass may be an effective method of reducing blood pressure (BP) levels in obese patients with hypertension, according to findings of the GATEWAY* trial presented at the AHA** 2017 Scientific Sessions.

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