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bronchitis%20-%20uncomplicated%20acute
BRONCHITIS - UNCOMPLICATED ACUTE
Uncomplicated acute bronchitis is a self-limiting infection of the trachea and bronchi that usually lasts for 1 to 3 weeks. A healthy patient experiences sudden onset of cough, with or without sputum production.
It is an inflammatory response to infections of the bronchial epithelium of the large airways of the lungs that begins with mucosal injury, epithelial cell damage and release of proinflammatory mediators.
There is transient airflow obstruction and bronchial hyperresponsiveness.
Purulence can result from either bacterial or viral infection.

Bronchitis - Uncomplicated Acute References

  1. European Study of Community-acquired Pneumonia (ESOCAP) Committee. Guidelines for management of adult community-acquired lower respiratory tract infections. Eur Respir J. 1998 Apr;11(4):986-991. doi: 10.1183/09031936.98.11040986. PMID: 9623709
  2. Braman SS. Chronic cough due to chronic bronchitis: ACCP evidence-based clinical practice guidelines. Chest. 2006 Jan;129(Suppl 1):95S-103S. doi: 10.1378/chest.129.1_suppl.95S. PMID: 16428698
  3. Gonzales R, Bartlett JG, Besser RE, et al. Principles of appropriate antibiotic use for treatment of uncomplicated acute bronchitis [background]. Ann Intern Med. 2001 Mar;134(6):521-529. doi: 10.7326/0003-4819-134-6-200103200-00021. PMID: 11255532
  4. Hirschmann JV. Antibiotics for common respiratory tract infections in adult. Arch Intern Med. 2002 Feb;162(3):256-264. doi: 10.1001/archinte.162.3.256. PMID: 11822917
  5. Knutson D, Braun C. Diagnosis and management of acute bronchitis. Am Fam Physician. 2002 May;65(10):2039-2044. PMID: 12046770
  6. Hueston WJ, Mainous AG 3rd. Acute bronchitis. Am Fam Physician. 1998 Mar;57(6):1270-1276,1281-1282. PMID: 9531910
  7. Macfarlane J, Holmes W, Gard P, et al. Reducing antibiotic use for acute bronchitis in primary care: blinded, randomised controlled trial of patient information leaflet. BMJ. 2002 Jan;324(7329):91-94. doi: 10.1136/bmj.324.7329.91. PMID: 11786454
  8. Massie RJ, Altunaji S, Kukurozovic R, et al. Pertussis: adults as a source in healthcare settings [letters]. Med J Aust. 2003 Feb;178(4):191. PMID: 12580755
  9. McCormack JG, Spearing NM, Horvath RL. Pertussis: adults as a source in healthcare settings [in reply to letters]. Med J Aust. 2003 Feb;178(4):191
  10. Ressel G; Centers for Disease Control and Prevention; American College of Physicians-American Society of Internal Medicine; American Academy of Family Physicians; Infectious Diseases Society of America. Principles of appropriate antibiotic use: part V. Acute bronchitis. Am Fam Physician. 2001 Sep;64(6):1098-1100. PMID: 11578027
  11. Spearing NM, Horvath RL, McCormack JG. Pertussis: adults as a source in healthcare settings. Med J Aust. 2002 Nov;177(10):568-569. https://www.mja.com.au/. PMID: 12429009
  12. Snow V, Mottur-Pilson C, Gonzales R; American Academy of Family Physicians; American College of Physicians-American Society of Internal Medicine; Centers for Disease Control; Infectious Diseases Society of America. Principles of appropriate antibiotic use for treatment of acute bronchitis in adults. Ann Intern Med. 2001 Mar;134(6):518-520. PMID: 11255531
  13. Wenzel RP, Fowler AA. Acute bronchitis. N Engl J Med. 2006 Nov;355(20):2125-2130. doi: 10.1056/NEJMcp061493. PMID: 17108344
  14. Gilbert DN, Moellering RC, Eliopoulos GM, et al. The Sanford guide to antimicrobial therapy. 35th. Hyde Park (VT): Antimicrobial Therapy Inc; 2005.
  15. Gwaltney Jr JM. Section C: acute bronchitis. In: Mandell GL, Bennett JE, Dolin R, eds. Mandell, Douglas and Bennett’s Principles and Practice of Infectious Diseases. 5th. Philadelphia: Elsevier Churchill Livingstone, Inc; 2000.
  16. Guide JK. Acute bronchitis. Conn's Current Therapy. 55th ed: Saunders, an imprint of Elsevier; 2003
  17. Gerberding JL. General principles and diagnostic approach. In: Mason RJ, Murray JF, Broaddus VC, et al. eds. Murray and Nadel’s Textbook of Respiratory Medicine. 3rd ed. Philadelphia: Lippincott Williams & Wilkins; 2000
  18. MedWormhttp://www.medworm.com/rss/index.php/Pediatrics/33/http://www.medworm.com/rss/medicalfeeds/specialities/Pediatrics.xml
  19. MedWormhttp://www.medworm.com/rss/index.php/Respiratory-Medicine/40/http://www.medworm.com/rss/medicalfeeds/specialities/Respiratory-Medicine.xml
  20. Scottish Intercollegiate Guidelines Network. Community management of lower respiratory tract infections in adults: a national clinical guideline. SIGN. http://www.sign.ac.uk. 2002.
  21. Ministry of Health Singapore. Clinical Practice Guidelines: use of antibiotics in adults. MOH (Singapore). http://www.moh.gov.sg/. Jan 2002.
  22. Alberta Medical Association. Guideline for the management and treatment of acute bronchitis. Alberta Medical Association. http://www.albertadoctors.com/. 2000.
  23. National Guideline Clearinghouse (NGC). Guideline summary: Management of uncomplicated acute bronchitis in adults. National Guideline Clearinghouse. http://www.guideline.gov/. Sep 2012. Accessed 10 Oct 2013.
  24. Woodhead M, Blasi F, Ewig S, et al. Guidelines for the management of adult lower respiratory tract infections – full version. Eur Respir J. 2011 Nov;17(Suppl 6):E1-E59. doi: 10.1111/j.1469-0691.2011.03672.x. Accessed 28 Nov 2018. PMID: 21951385
  25. Centers for Disease Control and Prevention. Adult treatment recommendations. CDC. https://www.cdc.gov/. Mar 2016.
  26. Harris AM, Hicks LA, Qaseem A; High Value Care Task Force of the American College of Physicians and for the Centers for Disease Control and Prevention. Appropriate antibiotic use for acute respiratory tract infection in adults: advice for high-value care from the American College of Physicians and the Centers for Disease Control and Prevention. Ann Intern Med. 2016 Mar;164(6):425-434. doi: 10.7326/M15-1840. PMID: 26785402
  27. Espallardo NL and PAFP QA Committee. Clinical pathways for the management of acute bronchitis in family and community practice. The Filipino Family Physician. Oct-Dec 2017;55(4):201-210.
  28. Alberta Medical Association. Toward Optimized Practice: guideline for the management of acute bronchitis. TOP (Toward Optimized Practice). http://www.topalbertadoctors.org. 2008. Accessed 28 Nov 2018.
  29. Albert RH. Diagnosis and treatment of acute bronchitis. Am Fam Physician. 2010 Dec;82(11):1345-1350. PMID: 21121518
  30. European Respiratory Society (ERS). Acute lower respiratory infections. European Lung white book. http://www.erswhitebook.org. 2018.
  31. File TM Jr. Patient education: acute bronchitis in adults (beyond the basics). UpToDate. http://www.uptodate.com. Sep 2017.
  32. File TM Jr. Acute bronchitis in adults. UpToDate. http://www.uptodate.com. Oct 2018.
  33. File TM Jr. Pertussis Rx and prophylaxis. UpToDate. http://www.uptodate.com. Oct 2018.
  34. Irwin RS, Baumann MH, Bolser DC. Diagnosis and management of cough executive summary: ACCP evidence-based clinical practice guidelines. Chest. 2006 Jan;129(Suppl 1):1S-23S. doi: 10.1378/chest.129.1_suppl.1S.
  35. Kinkade S, Long NA. Acute bronchitis. Am Fam Physician. 2016 Oct;94(7):560-565. PMID: 27929206
  36. Cornia P, Lipsky BA. Pertussis infection in adolescents and adults: clinical manifestations and diagnosis. UpToDate. http://www.uptodate.com. Dec 2018.
  37. Gonzales R, Sande MA. Uncomplicated acute bronchitis. Ann Intern Med. 2000 Dec;133(12):981-991. doi: 10.7326/0003-4819-133-12-200012190-00014. PMID: 11119400
  38. Murray MT. Bronchitis and pneumonia. In: Pizzornia JE, Murray MT, eds. Textbook of Natural Medicine. 4th. Philadelphia, PA: Saunders, Elsevier; 2013. http://dx.doi.org/10.1016/B978-1-4377-2333-5.00153-X. :1271-1276.
  39. National Institute for Health and Clinical Excellence. Respiratory tract infections – antibiotic prescribing: prescribing of antibiotics for self-limiting respiratory tract infections in adults and children in primary care. NICE. http://www.nice.org.uk. 2008.
  40. Sairenji T. Bronchitis and viral respiratory infections. In: Kellerman RD, Rakel DP, eds. Conn’s Current Therapy 2019. Philadelphia, PA: Saunders, Elsevier; 2019. http://dx.doi.org/10.1016/B978-0-323-59648-0.00187-5. :816-817.
  41. Walsh EE. Acute bronchitis. In: Bennet JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases. 8th. Philadelphia, PA: Saunders, Elsevier; 2015. http://dx.doi.org/10.1016/B978-0-323-40161-6.00066-8. :806-809.
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