Breast cancer is the presence of malignant breast nodule, mass or abscess.
Most common symptom of breast cancer is a new lump or mass in the
breast. The lump or mass is usually painless, hard & irregular but
it can also be tender, soft, rounded or painful.
Other signs & symptoms include breast pain or nipple pain, nipple
discharge, nipple retraction and presence of breast skin changes (eg
peau d' orange, nipple excoriation, scaling, inflammation, skin
tethering, ulceration, abscess).
In women who have undergone hysterectomy and use hormone therapy, the risk of invasive breast cancer does not differ significantly when directly comparing different doses, formulations and routes of delivery, according to a study.
Taking either one of the antihypertensive medications lisinopril or carvedilol when initiating treatment with trastuzumab did not appear to prevent heart function decline in patients with breast cancer, but a subgroup of patients who were also receiving anthracycline-based chemotherapy in addition to trastuzumab benefitted with a significantly reduced risk of heart damage, according to a study.
Post-menopausal women diagnosed with oestrogen receptor (ER)-positive ductal carcinoma in situ (DCIS) who undergo breast-conserving surgery followed by whole breast radiotherapy have a reduced risk of developing local recurrence, according to a study from Italy.
While neoadjuvant chemotherapy is comparable to adjuvant chemotherapy in reducing the risk of distant recurrence and mortality in women with early breast cancer, it is associated with a higher risk of local recurrence, according to a meta-analysis conducted by the EBCTCG*.
Survival outcomes of women diagnosed with breast cancer during pregnancy are similar to that of non-pregnant women, according to a presentation at ESMO Asia 2017. However, it is important to identify the dos and don’ts when diagnosing and treating breast cancer in this population.
Indication and demand for genetic testing have increased in recent years, with tests becoming more readily available and affordable, says a leading oncologist at ESMO Asia 2017, highlighting that appreciation of ethical, social, and legal implications of testing and proper test interpretation are important for optimal patient management.
Treatment with nebivolol yields more favourable changes in 24-hour, intradialytic and daytime systolic and diastolic blood pressure variability in patients with intradialytic hypertension, a study has found.
Early administration of recombinant human B-type natriuretic peptide (rhBNP) can lower the incidence of reperfusion injury for patients with ST-elevation myocardial infarction (STEMI) who are receiving percutaneous coronary intervention (PCI) treatment, according to a China study.
Intraoperative methylprednisolone does not appear to significantly prevent the incidence of death, cardiac arrest and other injuries in neonates undergoing cardiac surgery with cardiopulmonary bypass, according to a recent study.