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BLADDER CANCER
Treatment Guideline Chart

Bladder cancer is a heterogenous neoplasm that ranges from non-life-threatening, low-grade, superficial papillary lesions to high-grade invasive tumors that often metastasizes at the presentation.

It is the most common cancer involving the urinary system and it is the 11th most commonly diagnosed in the world.

Microscopic or gross painless hematuria is the most common presenting complaint.

Bladder Cancer References

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  2. Committee for Establishment of the Clinical Practice Guidelines for the Management of Bladder Cancer, Japanese Urological Association. Evidence-based clinical practice guidelines for bladder cancer (summary-JUA 2009 edition). Int J Urol. 2010 Feb;17(2):102-124. doi: 10.1111/j.1442-2042.2010.02486.x. Accessed 17 Dec 2015. PMID: 20377834
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  6. National Cancer Center Singapore. Bladder cancer. NCCS. http://www.nccs.com.sg/. 2015. Accessed 28 Jan 2016.
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  8. National Comprehensive Cancer Network. NCCN clinical practice guidelines on bladder cancer version 2.2015. NCCN. https://www.nccn.org. 2015. Accessed 17 Dec 2015.
  9. National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology (NCCN guidelines) - Asia consensus statements: bladder cancer. NCCN. http://www.nccn.org. 2016. Accessed 25 Jan 2016.
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  11. Witjes JA, Comperat E, Cowan NC, et al. Guidelines on muscle-invasive and metastatic bladder cancer. European Association of Urology. http://www.uroweb.org.guidelines/. Mar 2015. Accessed 28 Jan 2016.
  12. Witjes JA, Comperat E, Cowan NC, et al. Guidelines on muscle-invasive and metastatic bladder cancer. European Association of Urology. http://www.uroweb.org/guidelines/. 2016. Accessed 27 Jun 2016.
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  14. Babjuk M, Bohle A, Burger M, et al. Guidelines on non-muscle-invasive bladder cancer. European Association of Urology. http://www.uroweb.org/guidelines/. 2016. Accessed 27 Jun 2016.
  15. Babjuk M, Boehle A, Burger M, et al. EAU guidelines on non-muscle-invasive urothelial carcinoma of the bladder: update 2016. Eur Urol. 2017 Mar;71(3):447-461. doi: 10.1016/j.eururo.2016.05.041. PMID: 27324428
  16. Babjuk M, Burger M, Comperat E, et al. EAU Guidelines on non-muscle-invasive bladder cancer (TaT1 and CIS). European Association of Urology. https://www.uroweb.org/. Mar 2021. Accessed 02 Jul 2018.
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  18. Nishiyama H. Asia consensus statement on NCCN clinical practice guideline for bladder cancer. Jpn J Clin Oncol. 2018 Jan;48(1):3-6. doi: 10.1093/jjco/hyx130. PMID: 29145591
  19. Roupret M, Babjuk M, Comperat E, et al. European Association of Urology guidelines on upper urinary tract urothelial carcinoma: 2017 update. Eur Urol. 2018 Jan;73(1):111-122. doi: 10.1016/j.eururo.2017.07.036. PMID: 28867446
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  21. Witjes JA, Lebret T, Comperat EM, et al. Updated 2016 EAU guidelines on muscle-invasive and metastatic bladder cancer. Eur Urol. 2017 Mar;71(3):462-475. doi: 10.1016/j.eururo.2016.06.020. PMID: 27375033
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  25. Cancer Research UK. Bladder cancer statistics. Cancer Research UK. https://www.cancerresearchuk.org/. Mar 2020.
  26. ESMO Guidelines Committee. eUpdate – Bladder Cancer Treatment Recommendations. ESMO. http://www.esmo.org/. 16 Dec 2019.
  27. National Cancer Institute - Surveillance, Epidemiology, and End Results Program. Cancer stat facts: bladder cancer. NCI SEER. https://seer.cancer.gov/. 2020.
  28. National Comprehensive Cancer Network (NCCN). NCCN clinical practice guidelines in oncology (NCCN guidelines): Bladder cancer. Version 3.2020. NCCN. https://www.nccn.org/. 17 Jan 2020.
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  30. World Cancer Research Fund. Bladder cancer statistics. WCRF. https://www.wcrf.org/. 2020.
  31. Bellmunt J. Treatment of metastatic urothelial cancer of the bladder and urinary tract. UpToDate. https://www.uptodate.com. 21 Jun 2021.
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  33. ClinicalKey. Bladder cancer. ClinicalKey. https://www.clinicalkey.com. 20 May 2021.
  34. Witjes JA, Bruins HM, Cathomas R, et al. EAU Guidelines on muscle-invasive and metastatic bladder cancer. European Association of Urology. https://www.uroweb.org/. Mar 2021. Accessed 16 Jul 2021.
  35. Kulkarni GS, Black PC, Sridhar SS, et al. Canadian Urological Association guideline: Muscle-invasive bladder cancer. Can Urol Assoc J. 2019 Jan;13(8):230-238. doi: 10.5489/cuaj.5902. PMID: 30763236
  36. National Comprehensive Cancer Network. NCCN Clinical practice guidelines in oncology: bladder cancer, version 3.2021. NCCN. https://www.nccn.org/. 22 Mar 2021.
  37. U.S. Food and Drug Administration. Trodelvy prescribing information. US FDA. http://www.fda.gov. 2020.
  38. National Comprehensive Cancer Network (NCCN). NCCN Clinical practice guidelines in oncology: bladder cancer. Version 4.2021. NCCN. https://www.nccn.org/. 27 Jul 2021.
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