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BIPOLAR DISORDER

Bipolar I disorder is primarily defined by manic or mixed episodes that last for at least 7 days, or very severe manic symptoms needing immediate hospital care. The patient also has depressive episodes which may last for at least 2 weeks.
Bipolar II disorder is usually misdiagnosed. It is characterized by occurence of ≥1 major depressive episodes with at least 1 hypomanic episode.
Cyclothymic disorder or cyclothymia is a mild form of bipolar disorder. Patients have episodes of hypomania alternating with mild depression that lasts for 2 years.
Rapid-cycling bipolar disorder patients have ≥4 episodes of major depression, mania, hypomania or mixed symptoms within a year.

Bipolar Disorder Drug Information

Drug Information

Abilify Maintena

Aripiprazole

Indication: Maintenance treatment of schizophrenia in adult patients.

MIMS Class: Antipsychotics

Lundbeck / Otsuka [ Zuellig Pharma ]

Saphris

Asenapine

Indication: Schizophrenia. Mono- & adjunct therapy for acute treatment of manic or mixed episodes associated w/ bipola...

MIMS Class: Antipsychotics

Merck Sharp & Dohme / Lundbeck [ Zuellig Pharma ]

Clozaril

Clozapine

Indication: Patients w/ schizophrenia who are non-responsive to or intolerant of classic antipsychotics. Recurrent suicida...

MIMS Class: Antipsychotics

Mylan Healthcare [ DKSH ]

Invega

Paliperidone

Indication: Schizophrenia in adolescents ≥15 yr including acute treatment & recurrence prevention. Acute exacerbati...

MIMS Class: Antipsychotics

Janssen [ Zuellig Pharma ]

Invega Sustenna

Paliperidone

Indication: Acute & maintenance treatment of schizophrenia in adults. Schizoaffective disorder in adults as monotherap...

MIMS Class: Antipsychotics

Janssen [ Zuellig Pharma ]

Risperdal/Risperdal Consta

Risperidone

Indication: Risperdal Schizophrenia including 1st episode psychoses, acute schizophrenic exacerbations, chronic schizophre...

MIMS Class: Antipsychotics

Janssen [ Zuellig Pharma ]

Apalife 10/Apalife 15

Aripiprazole

Indication: Acute & maintenance treatment of schizoprenia. Acute manic episodes associated w/ bipolar I disorder.

MIMS Class: Antipsychotics

Unison [ Medispec ]

Arian

Aripiprazole

Indication: Schizophrenia & acute manic episodes w/ bipolar I disorder.

MIMS Class: Antipsychotics

Indoco Remedies [ Unimed ]

Lamictal

Lamotrigine

Indication: Adjunctive or monotherapy in treatment of epilepsy for partial & generalized seizures, including tonic-clo...

MIMS Class: Anticonvulsants

GlaxoSmithKline [ Zuellig Pharma ]

Olenza

Olanzapine

Indication: Acute & maintenance treatment of schizophrenia & other psychoses where +ve &/or -ve symptoms are p...

MIMS Class: Antipsychotics

Noripharma [ Pahang Pharmacy ]

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High dose comparable to lower doses of ACE inhibitors for heart failure

Jairia Dela Cruz, 16 Sep 2020

In patients with heart failure with reduced ejection fraction (HFrEF) receiving angiotensin-converting-enzyme (ACE) inhibitors, high dosing confers benefits for the risk of death or hospitalization that are similar to that obtained with lower dosing, according to a systematic review and meta-analysis.