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BENIGN PROSTATIC HYPERPLASIA
Treatment Guideline Chart
Benign prostatic hyperplasia (BPH) is a histopathological diagnosis characterized by epithelial cell & smooth muscle cell proliferation in the transition zone of the prostate leading to a non-malignant enlargement of the gland, which may result in lower urinary tract symptoms, including voiding and storage symptoms.
It is commonly called enlarged prostate.
The exact cause of BPH is still not well understood.

Benign Prostatic Hyperplasia References

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  2. Agency for Healthcare Research and Quality. Newer medications for lower urinary tract symptoms (LUTS) associated with Benign prostatic hyperplasia (BPH). Research Protocol – Apr 2015. AHQR. http://effectivehealthcare.ahrq.gov/index.cfm/search-for-guides-reviews-and-reports/?productid=2067&pageaction=displayproduct. Accessed 24 Aug 2015.
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  14. National Institute of Diabetes and Digestive and Kidney Diseases. Prostate enlargement: Benign prostatic hyperplasia. NIDDK. http://www.niddk.nih.gov/health-information/health-topics/urologic-disease/benign-prostatic-hyperplasia-bph/Pages/facts.aspx. Accessed 19 Aug 2015.
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  16. Otsuki H, Kosaka T, Nakamura K, et al. β3-Adrenoceptor agonist mirabegron is effective for overactive bladder that is unresponsive to antimuscarinic treatment or is related to benign prostatic hyperplasia in men. Int Urol Nephrol. 2013 Feb;45(1):53-60. doi: 10.1007/s11255-012-0343-5. Accessed 24 Aug 2015. PMID: 23212147
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  19. Zhang LT, Park JK. Are phosphodiesterase type 5 inhibitors effective for the management of lower urinary symptoms suggestive of benign prostatic hyperplasia?. World J Nephrol. 2015 Feb;4(1):138-147. doi: 10.5527/wjn.v4.i1.138. Accessed 20 Aug 2015. PMID: 25664256
  20. University of Maryland Medical Center. Benign prostatic hyperplasia. UMMC. http://umm.edu/health/medical/altmed/condition/benign-prostatic-hyperplasia. Accessed 22 Apr 2015.
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  26. Gravas S, Cornu JN, Drake MJ, et al. EAU guidelines on management of non-neurogenic male lower urinary tract symptoms (LUTS), incl. benign prostatic obstruction (BPO). European Association of Urology. https://uroweb.org. 2018.
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  34. Singapore Urological Association Male Lower Urinary Tract Symptoms/Benign Prostatic Hyperplasia Guidelines Committee 2015. Singapore Urological Association clinical guidelines for male lower urinary tract symptoms/benign prostatic hyperplasia. Singapore Med J. 2017 Aug;58(8):473-480. doi: 10.11622/smedj.2017082. PMID: 28848988
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  36. Elsevier Point of Care. Benign prostatic hypertrophy. ClinicalKey. https://www.clinicalkey.com. 31 Dec 2020.
  37. Parsons JK, Dahm P, Kohler TS, et al. Surgical management of lower urinary tract symptoms attributed to benign prostatic hyperplasia: AUA guideline amendment 2020. J Urol. 2020 Oct;204(4):799-804. doi: 10.1097/JU.0000000000001298. Accessed 09 Mar 2021. PMID: 32698710
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