Barrett's esophagus is defined as the endoscopic finding in the distal esophagus of proximal-appearing columnar-lined esophagus of at least 1-cm length that is confirmed by histology.
It is considered a premalignant metaplastic condition that usually involves the distal esophagus.
It is postulated that exposure of the esophageal epithelium to acid damages the lining resulting in chronic esophagitis and its healing involves metaplastic process.

Barrett's Esophagus References

  1. Fock KM, Talley N, Hunt R, et al. Report of the Asia-Pacific consensus on the management of gastroesophageal reflux disease. J Gastroenterol Hepatol. 2004 Apr;19(4):357-367. PMID: 15012771
  2. Sampliner RE, Practice Parameters Committee of the American College of Gastroenterology. Updated guidelines for the diagnosis, surveillance, and therapy of Barrett's esophagus. Am J Gastroenterol. 2002 Aug;97(8):1888-1895. PMID: 12190150
  3. DeVault KR, Castell DO, American College of Gastroenterology. Updated guidelines for the diagnosis and treatment of gastroesophageal reflux disease. Am J Gastroenterol. 2005 Jan;100(1):190-200. PMID: 15654800
  4. Wang KK, Sampliner RE. Updated guidelines 2008 for the diagnosis, surveillance and therapy of Barrett's esophagus. Am J Gastroenterol. 2008 Mar;103(3):788-797. doi: 10.1111/j.1572-0241.2008.01835.x. PMID: 18341497
  5. Spechler SJ. Clinical practice. Barrett's esophagus. N Engl J Med. 2002 Mar;346(11):836-842. PMID: 11893796
  6. Shalauta M, Saad R. Barrett's esophagus. Am Fam Physician. 2004 May;69(9):2113-2118. PMID: 15152957
  7. MedWorm
  8. Pharmacy Benefits Management Strategic Healthcare Group and the Medical Advisory Panel Veterans Health Administration Department of Veterans Affairs. VHA/DoD clinical practice guideline for the management of adults with gastroesophageal reflux disease in primary care practice. Mar 2003.
  9. American Gastroenterological Association, Spechler SJ, Sharma P, Souza RF, Inadomi JM, Shaheen NJ. American Gastroenterological Association medical position statement on the management of Barrett's esophagus. Gastroenterology. 2011 Mar;140(3):1084-1091. Accessed 21 Feb 2014. PMID: 21376940
  10. Booth CL, Thompson KS. Barrett's esophagus: a review of diagnostic criteria, clinical surveillance practices and new developments. J Gastrointest Oncol. 2012 Sep;3(3):232-242. Accessed 21 Feb 2014. PMID: 22943014
  11. Chang CY, Cook MB, Lee YC, et al. Current status of Barrett's esophagus research in Asia. J Gastroenterol Hepatol. 2011 Feb;26(2):240-246. Accessed 21 Feb 2014. PMID: 21155883
  12. Sharma P, Katzka D, Gupta N, et al. Quality indicators for the management of Barrett's esophagus, dysplasia and esophageal adenocarcinoma: international consensus recommendations from AGA symposium. Gastroenterology. 2015:1-24. doi: 10.1053/j.gastro.2015.08.00.
  13. Sollano JD, Romano RP, Ibanez-Guzman L, et al. Clinical practice guidelines on the diagnosis and treatment of gastroesophageal reflux disease (GERD). Philippine Journal of Internal Medicine. 2015 Jul-Sep;53(3):1-17. Accessed 02 Oct 2015
  14. Shaheen NJ, Falk GW, Iyer PG, et al; American College of Gastroenterology. ACG clinical guideline: diagnosis and management of Barrett's esophagus. Am J Gastroenterol. 2016 Jan;111(1):30-50. doi: 10.1038/ajg.2015.322. PMID: 26526079
  15. Fock KM, Talley N, Goh KL, et al. Asia-Pacific consensus on the management of gastro-oesophageal reflux disease: an update focusing on refractory reflux disease and Barrett's oesophagus. Gut. 2016 Sep;65(9):1402-1415. doi: 10.1136/gutjnl-2016-311715. PMID: 27261337
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