Barrett's esophagus is defined as the endoscopic finding in the distal esophagus of proximal-appearing columnar-lined esophagus of at least 1-cm length that is confirmed by histology.
It is considered a premalignant metaplastic condition that usually involves the distal esophagus.
It is postulated that exposure of the esophageal epithelium to acid damages the lining resulting in chronic esophagitis and its healing involves metaplastic process.
Elevated predicted levels of follicle-stimulating and luteinizing hormones are associated with a lower risk of Barrett’s oesophagus (BE), oesophageal adenocarcinoma (EAC), according to the results of a Mendelian randomization analysis.
A single use trasnasal endoscope, named EG Scan, is safe and highly accurate for detecting Barret’s oesophagus, with the sensitivity and specificity being higher than 90 percent, as compared with conventional esophagogastroduodenoscopy, according to a study.
Factors such as Barret’s oesophagus (BE) length, presence of low-grade dysplasia (LGD) and nodularity increase the risk of progression from nondysplastic (ND)BE or LGD to high-grade dysplasia or oesophageal adenocarcinoma, a study has found.
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