Autism involves impaired social interaction, impaired communication and lack of developmentally appropriate behavior, interests or activities.
Deficit in social skills eg abnormal eye contact, failure to orient name, failure to use gestures to point or show, lack of interactive play, failure to smile, lack of sharing & interest in other children, and often withdrawn and spends hours in solitary play with restrictive or repetitive interests and behaviors.
Impaired social interaction showed as impairment in joint attention, deficits in empathy for what another person might be feeling and deficits in understanding what another person might be thinking.
Autistic child also presents with deficit in language and communication (eg nonverbal or having some speech), aberrant play skills (eg little symbolic play, preoccupation with parts of objects), variation in intellectual functioning, heightened awareness to stimuli and lowered sensitivity to stimuli.
Greater screen exposure and less social play time in early life is associated with autism spectrum disorder (ASD)-like symptoms at age 2, although ASD risk was not increased, suggests an observational cohort study.
Individuals with co-occurring intellectual disabilities and autism appear to be in an unfavourable position, as they are more likely to have additional long-term health conditions such as sensory impairments and physical disabilities, as reported in a study.
While the SSRI fluoxetine appeared to improve obsessive-compulsive behaviours at 16 weeks compared with placebo in children and adolescents with autism spectrum disorders (ASD) in the initial analysis, the difference between groups became nonsignificant after correcting for potential confounding factors and imbalances in baseline characteristics, reveals the FAB* study.
Women with polycystic ovarian syndrome (PCOS) are at greater odds of having a child with autism spectrum disorder (ASD) and are more likely to be diagnosed with ASD themselves, according to the results of a meta-analysis.
In patients with heart failure with reduced ejection fraction (HFrEF) receiving angiotensin-converting-enzyme (ACE) inhibitors, high dosing confers benefits for the risk of death or hospitalization that are similar to that obtained with lower dosing, according to a systematic review and meta-analysis.