Atopic dermatitis or atopic eczema is a chronic, relapsing, familial, symmetric and pruritic inflammatory skin disease that commonly presents during early infancy and childhood, but can persist or start in adulthood.
It is commonly associated with elevated serum immunoglobulin E levels and a personal or family history of allergies, allergic rhinitis and asthma.
It is one of the most common skin diseases afflicting both children and adults.
Daily doses of the probiotic strains Bifidobacterium lactis CECT 8145, Bifidobacterium longum CECT 7347, and Lactobacillus casei CECT 9104 may reduce the SCORAD* index and need for topical steroids in children with moderate atopic dermatitis, according to a small study from Spain.
Eczema (atopic dermatitis) is a chronic inflammatory skin disease that
can present in many different forms. However, it is principally
characterized by dry skin, intense itching, and the presence of
inflammatory skin lesions. [J Eur Acad Dermatol Venereol
2016;30:604-618; N Engl J Med 2008;358:1483-1494; Lancet
Serum levels of squamous cell carcinoma antigen 2 (SCCA2) are indicative of disease severity and clinical type of atopic dermatitis (AD), according to a recent study, suggesting that SCCA2 may be a novel and useful marker for evaluating disease activity and treatment efficacy in AD.
There is a significant and disease severity‒dependent increased risk of developing conjunctivitis, keratitis and keratoconus in adults with atopic dermatitis (AD) compared with the general population, according to a recent study.
Patients with moderate-to-severe atopic dermatitis may benefit from a 52-week treatment course of dupilumab in addition to standard-of-care treatment, according to the results of the phase III LIBERTY AD CHRONOS* trial.
There is no evidence suggesting that genetically determined decrease in 25-hydroxyvitamin D (25OHD) levels confers an elevated risk of asthma, atopic dermatitis or elevated total serum immunoglobulin E (IgE), according to a recent study.
Low levels of vitamin D due to genetic polymorphism is not associated with increased risks of immune-mediated diseases such as asthma and atopic dermatitis, nor is it linked to increased total serum immunoglobulin E (IgE), in contrast to previous observations from epidemiological studies.
New drug applications approved by US FDA as of 16 - 31 March 2017 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
While exposure to UV light remains the top risk factor for skin cancer, other variables, such as smoking, immunosuppression and hypertension, also contribute to keratinocyte carcinoma, especially in nonwhite persons, a recent study has found.