Asthma is a chronic inflammatory disease of the airways in the lungs of children and adults.
The patient usually complains of shortness of breath, chest tightness and coughing with wheezing.
Goals of treatment are effective symptom control with minimal or no exacerbations, minimal or no nocturnal and daytime symptoms, no limitations on activities, minimal or no need for reliever treatment, and minimal adverse effects of medication.
Vitamin D therapy and bariatric surgery in obese asthmatic patients both improve peripheral blood mononuclear cells (PBMC) sensitivity to the in vitro corticosteroid (CS) treatment, results of a Spain study have shown.
Frequent coughing at night, measured using a smartphone app, appears to be a reliable indicator of worsening asthma, as reported in a study presented at this year’s European Respiratory Society (ERS) virtual meeting.
A short-term course of oral corticosteroid medication does not appear to improve disease control in patients with moderate to severe persistent asthma initiating treatment with inhaled corticosteroid-and-long-acting beta agonist (ICS-LABA).
The first-in-class tyrosine kinase inhibitor masitinib significantly reduces severe asthma exacerbations in patients who are uncontrolled on oral corticosteroids (OCS), regardless of their baseline eosinophil counts, according to a study presented at the ATS 2020 Virtual Meeting.
Treatment with the DPP 1* inhibitor brensocatib prolonged time to exacerbation and reduced exacerbation rates in patients with non-cystic fibrosis bronchiectasis, according to the phase II WILLOW** study presented at ERS 2020.
Almost three-quarters of adverse events (AEs) related to medication errors in over-the-counter (OTC) cough and cold medications (CCMs) for paediatrics required evaluation by healthcare facility and majority of the cases were due to dosing errors, a surveillance study has found, highlighting the need for interventions to mitigate medication errors.
A fixed-dose triple therapy of ICS, LAMA, and LABA* is superior to dual therapies of either LAMA-LABA or ICS-LABA for controlling exacerbations in patients with moderate-to-very-severe COPD**, according to the large ETHOS*** trial.