Asthma is a chronic inflammatory disease of the airways in the lungs of children and adults.
The patient usually complains of shortness of breath, chest tightness and coughing with wheezing.
A diagnosis of asthma in young children is more likely if they have
symptom patterns, presence of risk factors for development of asthma and
therapeutic response to controller treatment.
Goals of treatment are effective symptom control with minimal or no
exacerbations, minimal or no nocturnal and daytime symptoms, no
limitations on activities, minimal or no need for reliever treatment,
and minimal adverse effects of medication.
Children with controlled asthma and severe asthma appear to have slightly better school performances than their healthy counterparts, a recent study suggests. However, those with uncontrolled conditions perform worse.
In the management of children hospitalized with severe asthma exacerbations, preservative-free albuterol formulations are safer for use in continuous nebulization compared with a benzalkonium chloride (BAC)-containing formulation, which is associated with longer treatment duration and additional respiratory support, as shown in a recent study.
Frequent exposure to household cleaning products during early life is associated with a greater risk of childhood asthma and wheeze at age 3 years, according to the CHILD* cohort study — adding to the growing call to action on the risk of cleaning products as irritants for airways of young children.
Children of women who had asthma exacerbations during pregnancy were more likely have respiratory disorders such as asthma and pneumonia than those whose mothers did not — suggesting that the effects of asthma exacerbations during pregnancy may transcend generations, a study finds. This was in addition to having an increased risk of adverse pregnancy and perinatal outcomes.
Having supportive family relationships may help youth maintain good asthma management behaviours despite difficult neighbourhood conditions--thus serving as a buffer against poor asthma outcomes associated with living in disorderly neighbourhoods, a recent study finds.
A self-monitoring application for children with asthma, namely the electronic-AsthmaTracker (e-AT), appears to effectively involve parents in the proactive care of their children, leading to sustained improvement in outcomes, as shown in a recent study.
Dietary intake of the fatty acids (FAs) omega-3 and omega-6 was associated with opposing effects in severity of childhood asthma and susceptibility to environmental pollutants, suggests the AsthmaDIET study.
Routinely used for treating cardiovascular diseases, statins have been shown to benefit other conditions, and new evidence suggests that using the drug at high intensity reduces the risk of hip or knee replacement, an effect that may be specific to rheumatoid arthritis.
Having migraine during midlife appears to be associated with a higher risk of developing dementia in later life, according to a large population-based longitudinal Danish study presented at the AHS* 2020 Virtual Meeting, indicating that migraine may be a risk factor for dementia.
Upadacitinib may be a suitable treatment for patients with active psoriatic arthritis (PsA) who have insufficient response to non-biologic disease-modifying anti-rheumatic drugs (non-bDMARDs), according to results of the phase III SELECT-PsA-1* trial presented at EULAR 2020.