anemia%20-%20iron-deficiency%20(pediatric)
ANEMIA - IRON-DEFICIENCY (PEDIATRIC)

Iron deficiency (ID) is the most common nutritional deficiency in children & reportedly 3x more common than iron-deficiency anemia, but does not always develop into anemia.

Neonates & children may have delayed growth & development; adolescents may show decrements of learning such as behavioral abnormalities.

Iron-deficiency anemia is the most advanced stage of iron deficiency resulted from a protracted imbalance between iron intake & demand.

Characterized by low hemoglobin & hematocrit levels, reduction or depletion of iron stores, low serum iron levels & decreased transferrin saturation.

Anemia - Iron-Deficiency (Pediatric) References

  1. Goddard AF, James MW, McIntyre AS, Scott BB; British Society of Gastroenterology. Guidelines for the management of iron deficiency anaemia. Gut. 2011 Oct;60(10):1309-1316. doi: 10.1136/gut.2010.228874. PMID: 21561874
  2. Hadi F. Iron supplementation and therapy for children: simple measures to achieve brighter generation. MIMS. http://staging.pubportal.mims.com/topic/iron-supplementation-and-therapy-for-children--simple-measures-to-achieve-brighter-generation?country=singapore&channel=paediatrics&topicGrouper=. Dec 2015.
  3. Baker RD, Greer FR; Committee on Nutrition American Academy of Pediatrics. Diagnosis and prevention of iron deficiency and iron-deficiency anemia in infants and young children (0-3 years of age). Pediatrics. 2010 Nov;126(5):1040-1050. doi: 10.1542/peds.2010-2576. PMID: 20923825
  4. Lichtin A. Iron-deficiency anemia. First Consult. https://www.clinicalkey.com/#!/content/medical_topic/21-s2.0-1014692. Oct 2012.
  5. Mahoney DH. Iron deficiency in infants and young children: Screening, prevention, clinical manifestations, and diagnosis. UpToDate. http://www.uptodate.com/contents/iron-deficiency-in-infants-and-young-children-screening-prevention-clinical-manifestations-and-diagnosis. Jun 2016.
  6. National Health and Medical Research Council (NHMRC), Department of Health and Ageing, Australia. Nutrient reference values for Australia and New Zealand: including recommended dietary intakes. NHMRC. https://www.nhmrc.gov.au/_files_nhmrc/publications/attachments/n35.pdf. Sep 2005.
  7. National Institutes of Health. Iron: dietary supplement fact sheet. NIH. https://ods.od.nih.gov/factsheets/Iron-HealthProfessional/#h2. Feb 2016.
  8. Santiago P. Ferrous versus ferric oral iron formulations for the treatment of iron deficiency: a clinical overview. ScientificWorldJournal. 2012 May;2012(846824). doi: 10.1100/2012/846824. PMID: 22654638
  9. Schrier S, Auerbach M. Treatment of iron deficiency anemia in adults. UpToDate. http://www.uptodate.com/contents/treatment-of-iron-deficiency-anemia-in-adults. Jul 2016.
  10. Short MW, Domagalski JE. Iron deficiency anemia: evaluation and management. Aust Fam Physician. 2013 Jan;87(2):98-104. http://www.aafp.org/afp/2013/0115/p98.html. PMID: 23317073
  11. Vehapoglu A, Ozgurhan G, Demir AD, et al. Hematological indices for differential diagnosis of Beta thalassemia trait and iron deficiency anemia. Anemia. 2014;2014(576738). doi: 10.1155/2014/576738. PMID: 24818016
  12. World Health Organization. Guideline: Daily iron supplementation in infants and children. Geneva: World Health Organization Press; 2016.
Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS JPOG - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
01 Dec 2020
Tetanus toxoid 5 Lf, diphtheria toxoid 2 Lf, pertussis toxoid 2.5 mcg, filamentous haemagglutinin 5 mcg, fimbriae types 2 and 3 5 mcg, pertactin 3 mcg
Dr. Hsu Li Yang, Dr. Tan Thuan Tong, Dr. Andrea Kwa, 08 Jan 2021
Antimicrobial resistance has become increasingly dire as the rapid emergence of drug resistance, especially gram-negative pathogens, has outpaced the development of new antibiotics. At a recent virtual symposium, Dr Hsu Li Yang, Vice Dean (Global Health) and Programme Leader (Infectious Diseases), NUS Saw Swee Hock School of Public Health, presented epidemiological data on multidrug-resistant (MDR) gram-negative bacteria (GNB) in Asia, while Dr Tan Thuan Tong, Head and Senior Consultant, Department of Infectious Diseases, Singapore General Hospital (SGH), focused on the role of ceftazidime-avibactam in MDR GNB infections. Dr Andrea Kwa, Assistant Director of Research, Department of Pharmacy, SGH, joined the panel in an interactive fireside chat, to discuss challenges, practical considerations, and solutions in MDR gram-negative infections. This Pfizer-sponsored symposium was chaired by Dr Ng Shin Yi, Head and Senior Consultant of Surgical Intensive Care, SGH.
Pearl Toh, 26 Nov 2020
Inhaled corticosteroid (ICS) should be the mainstay of long-term asthma management — such is the key message of the latest Singapore ACE* Clinical Guidance (ACG) for asthma, released in October 2020.
Audrey Abella, 6 days ago
A pilot telemedicine initiative may be an alternative for facilitating delivery of intravenous iron (IVI) for individuals requiring iron supplementation.