Paediatrics Search
Paediatrics Paediatrics
anemia%20-%20iron-deficiency%20(pediatric)
ANEMIA - IRON-DEFICIENCY (PEDIATRIC)

Iron deficiency (ID) is the most common nutritional deficiency in children & reportedly 3x more common than iron-deficiency anemia, but does not always develop into anemia.

Neonates & children may have delayed growth & development; adolescents may show decrements of learning such as behavioral abnormalities.

Iron-deficiency anemia is the most advanced stage of iron deficiency resulted from a protracted imbalance between iron intake & demand.

Characterized by low hemoglobin & hematocrit levels, reduction or depletion of iron stores, low serum iron levels & decreased transferrin saturation.

  1. Goddard AF, James MW, McIntyre AS, Scott BB; British Society of Gastroenterology. Guidelines for the management of iron deficiency anaemia. Gut. 2011 Oct;60(10):1309-1316. doi: 10.1136/gut.2010.228874. PMID: 21561874
  2. Hadi F. Iron supplementation and therapy for children: simple measures to achieve brighter generation. MIMS. http://staging.pubportal.mims.com/topic/iron-supplementation-and-therapy-for-children--simple-measures-to-achieve-brighter-generation?country=singapore&channel=paediatrics&topicGrouper=. Dec 2015.
  3. Baker RD, Greer FR; Committee on Nutrition American Academy of Pediatrics. Diagnosis and prevention of iron deficiency and iron-deficiency anemia in infants and young children (0-3 years of age). Pediatrics. 2010 Nov;126(5):1040-1050. doi: 10.1542/peds.2010-2576. PMID: 20923825
  4. Lichtin A. Iron-deficiency anemia. First Consult. https://www.clinicalkey.com/#!/content/medical_topic/21-s2.0-1014692. Oct 2012.
  5. Mahoney DH. Iron deficiency in infants and young children: Screening, prevention, clinical manifestations, and diagnosis. UpToDate. http://www.uptodate.com/contents/iron-deficiency-in-infants-and-young-children-screening-prevention-clinical-manifestations-and-diagnosis. Jun 2016.
  6. National Health and Medical Research Council (NHMRC), Department of Health and Ageing, Australia. Nutrient reference values for Australia and New Zealand: including recommended dietary intakes. NHMRC. https://www.nhmrc.gov.au/_files_nhmrc/publications/attachments/n35.pdf. Sep 2005.
  7. National Institutes of Health. Iron: dietary supplement fact sheet. NIH. https://ods.od.nih.gov/factsheets/Iron-HealthProfessional/#h2. Feb 2016.
  8. Santiago P. Ferrous versus ferric oral iron formulations for the treatment of iron deficiency: a clinical overview. ScientificWorldJournal. 2012 May;2012(846824). doi: 10.1100/2012/846824. PMID: 22654638
  9. Schrier S, Auerbach M. Treatment of iron deficiency anemia in adults. UpToDate. http://www.uptodate.com/contents/treatment-of-iron-deficiency-anemia-in-adults. Jul 2016.
  10. Short MW, Domagalski JE. Iron deficiency anemia: evaluation and management. Aust Fam Physician. 2013 Jan;87(2):98-104. http://www.aafp.org/afp/2013/0115/p98.html. PMID: 23317073
  11. Vehapoglu A, Ozgurhan G, Demir AD, et al. Hematological indices for differential diagnosis of Beta thalassemia trait and iron deficiency anemia. Anemia. 2014;2014(576738). doi: 10.1155/2014/576738. PMID: 24818016
  12. World Health Organization. Guideline: Daily iron supplementation in infants and children. Geneva: World Health Organization Press; 2016.
Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS JPOG - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Dolutegravir: Towards an Optimized Treatment in the Management of HIV
19 Jun 2019
Acquired immunodeficiency syndrome (AIDS) remains as one of the world’s leading causes of mortality in global public health. Dr Charles Hicks shared his insights into the increasing role of dolutegravir (DTG; Tivicay, GSK) – an integrase strand transfer inhibitor (INSTI) – in HIV therapy during the 4th National AIDS Conference 2018 at Swiss Garden International Hotel and Residences, Kuala Lumpur.
Tenofovir disoproxil fumarate monotherapy improves virologic response in HBV patients
2 days ago
Monotherapy with tenofovir disoproxil fumarate increases virologic response for up to 240 weeks in pretreated patients with hepatitis B virus infection (HBV) who are resistant to entecavir and/or adefovir, a new study has found.
Long-term use of benralizumab efficacious, safe for severe, uncontrolled asthma
Elvira Manzano, 3 days ago
Long-term treatment with the interleukin-5 receptor alpha-directed cytolytic monoclonal antibody benralizumab led to long-term control of asthma, improvement in pulmonary function, and was safe in patients with severe eosinophilic asthma in the 2-year integrated analysis of the SIROCCO, CALIMA, and ZONDA pivotal studies plus the BORA extension study reported at ATS 2019.
RA remission and CV protection go hand in hand
Pearl Toh, 11 hours ago
Patients with rheumatoid arthritis (RA) who maintained their disease remission had a significantly reduced risk of clinical and subclinical atherosclerosis, according to the 3-year follow-up data of the GIRRCS* study presented at EULAR 2019.