anemia%20-%20iron-deficiency%20(pediatric)
ANEMIA - IRON-DEFICIENCY (PEDIATRIC)

Iron deficiency (ID) is the most common nutritional deficiency in children & reportedly 3x more common than iron-deficiency anemia, but does not always develop into anemia.

Neonates & children may have delayed growth & development; adolescents may show decrements of learning such as behavioral abnormalities.

Iron-deficiency anemia is the most advanced stage of iron deficiency resulted from a protracted imbalance between iron intake & demand.

Characterized by low hemoglobin & hematocrit levels, reduction or depletion of iron stores, low serum iron levels & decreased transferrin saturation.

  1. Goddard AF, James MW, McIntyre AS, Scott BB; British Society of Gastroenterology. Guidelines for the management of iron deficiency anaemia. Gut. 2011 Oct;60(10):1309-1316. doi: 10.1136/gut.2010.228874. PMID: 21561874
  2. Hadi F. Iron supplementation and therapy for children: simple measures to achieve brighter generation. MIMS. http://staging.pubportal.mims.com/topic/iron-supplementation-and-therapy-for-children--simple-measures-to-achieve-brighter-generation?country=singapore&channel=paediatrics&topicGrouper=. Dec 2015.
  3. Baker RD, Greer FR; Committee on Nutrition American Academy of Pediatrics. Diagnosis and prevention of iron deficiency and iron-deficiency anemia in infants and young children (0-3 years of age). Pediatrics. 2010 Nov;126(5):1040-1050. doi: 10.1542/peds.2010-2576. PMID: 20923825
  4. Lichtin A. Iron-deficiency anemia. First Consult. https://www.clinicalkey.com/#!/content/medical_topic/21-s2.0-1014692. Oct 2012.
  5. Mahoney DH. Iron deficiency in infants and young children: Screening, prevention, clinical manifestations, and diagnosis. UpToDate. http://www.uptodate.com/contents/iron-deficiency-in-infants-and-young-children-screening-prevention-clinical-manifestations-and-diagnosis. Jun 2016.
  6. National Health and Medical Research Council (NHMRC), Department of Health and Ageing, Australia. Nutrient reference values for Australia and New Zealand: including recommended dietary intakes. NHMRC. https://www.nhmrc.gov.au/_files_nhmrc/publications/attachments/n35.pdf. Sep 2005.
  7. National Institutes of Health. Iron: dietary supplement fact sheet. NIH. https://ods.od.nih.gov/factsheets/Iron-HealthProfessional/#h2. Feb 2016.
  8. Santiago P. Ferrous versus ferric oral iron formulations for the treatment of iron deficiency: a clinical overview. ScientificWorldJournal. 2012 May;2012(846824). doi: 10.1100/2012/846824. PMID: 22654638
  9. Schrier S, Auerbach M. Treatment of iron deficiency anemia in adults. UpToDate. http://www.uptodate.com/contents/treatment-of-iron-deficiency-anemia-in-adults. Jul 2016.
  10. Short MW, Domagalski JE. Iron deficiency anemia: evaluation and management. Aust Fam Physician. 2013 Jan;87(2):98-104. http://www.aafp.org/afp/2013/0115/p98.html. PMID: 23317073
  11. Vehapoglu A, Ozgurhan G, Demir AD, et al. Hematological indices for differential diagnosis of Beta thalassemia trait and iron deficiency anemia. Anemia. 2014;2014(576738). doi: 10.1155/2014/576738. PMID: 24818016
  12. World Health Organization. Guideline: Daily iron supplementation in infants and children. Geneva: World Health Organization Press; 2016.
Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS JPOG - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
3 days ago

Dr Michael Lim, a senior consultant at the Paediatric Pulmonary and Sleep Division, National University Hospital, Singapore, speaks to Roshini Claire Anthony on the rare disease that is cystic fibrosis.

Yesterday
Susceptibility‐guided therapy is as effective as empiric modified bismuth quadruple therapy for the first-line treatment of Helicobacter pylori infection, with both yielding excellent eradication rates, as shown in a recent trial.
3 days ago
It appears that long-term consumption of fish and omega-3 fatty acid does not influence the risk of incident hypertension in middle-aged and older men, suggests a US study.
Yesterday
The risk factors and outcomes associated with an increased risk of permanent pacing include atrial fibrillation (AF) ablation, multivalve surgery and New York Heart Association (NYHA) functional class III/IV, a recent study has found.