Anaphylaxis is a serious generalized or systemic hypersensitivity reaction that is rapid in onset and potentially fatal.
Diagnosis can be made if it is acute in onset of minute to several hour
duration that involves the skin, mucosal tissue or both plus having
signs & symptoms either respiratory or cardiovascular compromise.
It involves immunological response with IgE, IgG or immune complexes.
Non-immunological mechanisms are also involved and termed as nonallergic
anaphylaxis that is relatively uncommon in children.
Protracted, severe anaphylaxis are reactions occurring up to 32 hours despite aggressive management.
Use of standard-dose aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) appears to confer protection against the risk of endometrial cancer in overweight and obese women, according to a meta-analysis.
Less than 15 percent of Singaporean adolescents get the recommended 8–10 hours of sleep on a school night, reports a recent study, noting that such short sleep duration is linked to symptoms of depression, overweight or obesity, and poorer self-rated health.
Obstructive sleep apnoea may increase the risk of male-pattern baldness in men with a family history of hair loss, and this association appears to be mediated by low serum transferrin saturation levels related to hypoxia, a study suggests.