Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease with undetermined etiology that primarily involves the motor neurons in the cerebral cortex, brainstem and spinal cord.
There is no cure and the mean duration of survival is 2-5 years without tracheostomy and ventilator support.
Clinical hallmarks of ALS are: presence of upper & lower motor neuron features involving the brainstem and spinal cord and progressive limb weakness, respiratory insufficiency, spasticity, hyperreflexia, and bulbar symptoms such as dysarthria and dysphagia.
Similarities in insulin signaling mechanisms between the brains of Alzheimer’s disease patients and the pancreas of diabetic patients may point the way to improved treatment for the former, according to researchers.
High-resistant starch, low-protein flour improves blood glucose and lipid levels among people with early type 2 diabetic neuropathy, as well as improves their ability to prevent antioxidative stress, reports a recent study.