Alcoholic liver disease diagnosis is suggested by an established history of habitual alcohol intake of sufficient length and intensity.
Toxic daily threshold of alcohol consumption is 40-80 g for males and 20-40 g for females for 10-12 years.
Signs of alcohol abuse and hepatic injury include malnutrition and muscle wasting, cutaneous telangiectasia, palmar erythema, finger clubbing, Dupuytren's contracture, peripheral neuropathy, parotid gland enlargement and signs of gynecomastia and hypogonadism may also be present.

Surgical Intervention

Liver Transplantation

  • Patients with advanced alcoholic liver disease (ALD) or end-stage liver disease secondary to alcoholic cirrhosis may be considered for liver transplantation
  • Survival rate is comparable to patients who had transplantation from nonalcoholic liver disease
    • Patients classified as Child-Pugh C and/or MELD >15 gain survival benefit
  • Carefully evaluate the patient for:
    • Ability and commitment to abstain from alcohol
    • Damage to other organs (eg heart, brain)
    • Malignancy in the upper gastrointestinal tract or the upper airways
Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Gastroenterology - Malaysia digital copy today!
Editor's Recommendations
Most Read Articles
31 Jan 2018
Treatment with proton pump inhibitors (PPIs) appears to increase the risk of death during hospitalization in the presence of pyogenic liver abscess, according to a study.
28 Jun 2017
Intra- and/or postoperative blood transfusion (BT) may increase the risk of postoperative infections complications in patients with Crohn’s disease (CD), according to a study.
18 Oct 2016
EndoClot has been shown to help in the management of gastrointestinal (GI) bleeding whether as a monotherapy or in combination with other techniques from oozing bleeding type or lower, according to a recent study.
Stephen Padilla, 22 Dec 2017
A correlation exists between coeliac disease and a heightened risk of pneumococcal infection, according to a recent study, adding that vaccination must be considered for those with the disease, especially those aged 15‒64 years who have not received the scheduled pneumococcal vaccination series when they were young.