alcoholic%20liver%20disease
ALCOHOLIC LIVER DISEASE
Alcoholic liver disease diagnosis is suggested by an established history of habitual alcohol intake of sufficient length and intensity.
Toxic daily threshold of alcohol consumption is 40-80 g for males and 20-40 g for females for 10-12 years.
Signs of alcohol abuse and hepatic injury include malnutrition and muscle wasting, cutaneous telangiectasia, palmar erythema, finger clubbing, Dupuytren's contracture, peripheral neuropathy, parotid gland enlargement and signs of gynecomastia and hypogonadism may also be present.

Introduction

Patient may present with signs and symptoms related to portal hypertension:
  • Abdominal wall collaterals
  • Ascites
  • Splenomegaly
  • Venous hum

Signs and Symptoms

Signs of Alcohol Abuse and Hepatic Injury

  • Malnutrition and muscle wasting
  • Cutaneous telangiectasia
  • Palmar erythema
  • Finger clubbing
  • Dupuytren’s contracture
  • Peripheral neuropathy
  • Parotid gland enlargement
  • Signs of gynecomastia and hypogonadism may also be present

Others

  • Hepatomegaly, which is the most common sign in patients with alcoholic liver disease (ALD)
  • Patient may be asymptomatic
  • Alcohol withdrawal
  • Jaundice
  • Anorexia, weight loss
  • Hepatic encephalopathy
Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Gastroenterology - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
13 Mar 2017
The serum pepsinogen test—which is relatively simple, inexpensive, sensitive and specific—is a potentially viable method for the screening and detection of Kazakh early gastric cancer, a new study claims.
24 Apr 2017

Helicobacter pylori (H. pylori) infection is associated with conditions such as gastritis, peptic ulcer, gastric cancer, and certain types of lymphoma. A common presenting complaint among all these H. pylori-related illnesses is dyspepsia. Dr Desmond Wai from the Desmond Wai Liver and Gastrointestinal Diseases Centre, Mount Elizabeth Novena Specialist Centre, Singapore, speaks on the important role general practitioners (GPs) play in recognizing, diagnosing, and treating H. pylori.

Pearl Toh, 24 Nov 2016
New treatments such as pirfenidone and nintedanib slow lung function decline and progression of idiopathic pulmonary fibrosis (IPF), although response to treatment can vary dramatically among patients, according to a presentation at the 21st Congress of the Asian Pacific Society of Respirology (APSR 2016) held in Bangkok, Thailand.