age-related%20macular%20degeneration
AGE-RELATED MACULAR DEGENERATION
Age-related macular degeneration is a common, chronic, progressive, degenerative disease that causes central loss of vision due to abnormalities that occurs in the pigment, neural and vascular layers of the macula.
The macular disorder may have one or more of the following:
- Formation of drusen which are localized deposits of extracellular material usually concentrated in the macula
- Abnormalities in the retinal pigment epithelium (eg hypopigmentation or hyperpigmentation)
- Retinal pigment epithelium and choriocapillaris geographic atrophy
- Neovascular (exudative) maculopathy
Decreased central vision and distortion of seeing straight lines are the most common symptoms.

Patient Education

  • Instruct patients with age-related macular degeneration (AMD) on how to test their vision daily or at least weekly
    • While patients with exudative AMD or have had laser treatment, should be instructed on how to monitor the size of their blind spots or the appearance of new ones
  • Encourage high risk patients (eg with early AMD and/or family history of AMD) to have regular dilated eye exams for the early detection of the intermediate stage of AMD
  • For low risk patients, it is recommended to have comprehensive medical eye evaluation schedule as below:
    • Patients 40-54 years old every 2-4 years
    • Patients 55-64 years old every 1-3 years
    • Patients ≥65 years old every 1-2 years
  • Patients should be informed about the symptoms of progressing choroidal neovascularization (CNV) (eg progressive decrease in central vision) and counsel on the need for prompt consultation with an ophthalmologist
  • Smoking cessation should be done as this is the main modifiable risk factor for AMD
  • Diet that includes leafy green vegetables, fresh fruits and fishes rich in omega-3 fatty acids may help decrease the risk for AMD
  • Maintain an ideal body weight
    • Increased body mass index (BMI) and abdominal obesity have increased risk for AMD
  • Wear sunglasses with 100% protection against ultraviolet A and B (UVA and UVB) radiation in bright environments
Editor's Recommendations
Most Read Articles
4 days ago
Combining the DASH (Dietary Approaches to Stop Hypertension) diet with low sodium intake reduces systolic blood pressure (SBP) in individuals with pre- and stage 1 hypertension, with progressively higher reductions at greater levels of baseline SBP, a recent study has shown.
Tristan Manalac, 2 days ago
Major depressive disorder (MDD) appears to be more prevalent in females than in males, particularly in those who are divorced or widowed, a recent study from Singapore has found.
3 days ago
Tadalafil may not be effective for reducing the decline in ambulatory ability in boys with Duchenne muscular dystrophy (DMD), as shown in a recent study.
6 days ago
Hydrochlorothiazide (HCTZ) appears to significantly increase the risks of nonmelanoma skin cancer (NMSC), particularly squamous cell carcinoma (SCC), a recent study has shown.