acne%20vulgaris
ACNE VULGARIS
Acne vulgaris is a chronic inflammatory dermatosis which is notable for open and/or closed comedones (blackheads and whiteheads) and inflammatory lesions including papules, pustules or nodules.
Mild acne has <20 comedones or <15 inflammatory lesions or <30 total lesion count.
Moderate acne has 20-100 comedones or 15-20 inflammatory lesions or 30-125 total lesion count.
Severe papules/pustules or nodulocystic acne is the acne resistant to topical treatment or if scarring/nodular lesions are present.
  1. Bershad SV. The modern age of acne therapy: a review of current treatment options. Mount Sinai J Med. 2001 Sep/Oct;68(4 & 5):279-286. http://www.ncbi.nlm.nih.gov/pubmed/?term=Bershad+SV%09The+modern+age+of+acne+therapy%3A+a+review+of+current+treatment+options. PMID: 11514915
  2. Del Rosso JQ, Kim G. Optimizing use of oral antibiotics in acne vulgaris. Dermatol Clin. 2009 Jan;27(1):33-42. doi: 10.1016/j.det.2008.07.006. PMID: 18984366
  3. Clarke SB, Nelson AM, George RE, et al. Pharmacologic modulation of sebaceous gland activity: mechanisms and clinical applications. Dermatol Clin. 2007 Apr;25(2):137-146. PMID: 17430751
  4. Dawson AL, Dellavalle RP. Acne vulgaris. BMJ. 2013 May;346:d2634. doi: 10.1136/bmj.f2634. Accessed 26 Jul 2013. PMID: 23657180
  5. Feldman S, Careccia RE, Barham KL,et al. Diagnosis and treatment of acne. Am Fam Physician. 2004 May;69(9):2123-2130. PMID: 15152959
  6. Johnson BA, Nunley JR. Use of systemic agents in the treatment of acne vulgaris. Am Fam Physician. 2000 Oct;62(8):1823-1830,1835-1836. PMID: 11057839
  7. Liao DC. Management of Acne. J Fam Pract. 2003 Jan;52(1):43-51. PMID: 12540312
  8. Nestor MS. The use of photodynamic therapy for treatment of acne vulgaris. Dermatol Clin. 2007 Jan;25(1):47-57. PMID: 17126741
  9. Lehmann HP, Robinson KA, Andrews JS, et al. Acne therapy: a methodologic review. J Am Acad Dematol. 2002 Aug;47(2):231-240. PMID: 12140469
  10. Krowchuck DP. Treating acne: a practical guide. Med Clin North Am. 2000 Jul;84(4):811-828. PMID: 10928190
  11. Thiboutot D, Gollnick H, Bettoli V, et al. New insights into the management of acne: an update from the Global Alliance to Improve Outcomes in Acne group. J Am Acad Dematol. 2009 May;60(5 Suppl):S1-S50. doi: 10.1016/j.jaad.2009.01.019. PMID: 19376456
  12. Thiboutot D. New treatments and therapeutic strategies for acne. Arch Fam Med. 2000 Feb;9(2):179-187. PMID: 10693736
  13. Strauss JS, Krowchuk DP, Leyden JJ, et al. Guidelines of care for acne vulgaris management. J Am Acad Dermatol. 2007 Apr;56(4):651-663. PMID: 17276540
  14. Sinclair W, Jordaan HF. Acne guideline 2005 update. S Afr Med J. 2005 Nov;95:881-892. PMID: 16344888
  15. Titus S, Hodge J. Diagnosis and treatment of acne. Am Fam Physician. 2012 Oct;86(8):734-740. Accessed 29 Jul 2013. PMID: 23062156
  16. Usatine RP, Quan MA. Pearls in the management of acne: an advanced approach. Prim Care. 2000 Jun;27(2):289-308. PMID: 10815044
  17. Webster GF. Acne vulgaris. BMJ. 2002 Aug;325(7362):475-479. PMID: 12202330
  18. Yan AC. Current concepts in acne management. Adolesc Med Clin. 2006 Oct;17(3):613-637. PMID: 17030282
  19. Gilbert DN, Moellering RC, Eliopoulos GM, et al. The Sanford guide to antimicrobial therapy. 40th. Sperryville, VA: Antimicrobial Therapy Inc; 2010.
  20. Gilbert DN, Moellering RC, Eliopoulos GM, et al. The Sanford guide to antimicrobial therapy. 37th ed. Sperryville, VA: Antimicrobial Therapy Inc; 2007
  21. Habif TP. Acne, Rosacea, and Related Disorders. Clinical dermatology: A color guide to diagnosis and therapy. 4th ed. Pennsylvania: Mosby, Elsevier; 2004
  22. MedWorm http://www.medworm.com/rss/index.php/Dermatology/12/ http://www.medworm.com/rss/medicalfeeds/specialities/Dermatology-News.xml
  23. Graber E. Treatment of acne vulgaris. UpToDate. https://www.uptodate.com. 21 Oct 2019. Accessed 29 Jul 2013.
  24. Gutiérrez RM, Mitchell S, Solis RV. Psidium guajava: a review of its traditional uses, phytochemistry and pharmacology. J Ethnopharmacol. 2008 Apr 17;117(1):1-27. http://www.sciencedirect.com/science/article/pii/S0378874108000536. PMID: 18353572
  25. Goh CL, Noppakun N, Micali G, et al. Meeting the challenges of acne treatment in Asian patients: a review of the role of dermocosmetics as adjunctive therapy. J Cutan Aesthet Surg. 2016 Apr-Jun;9(2):85–92. doi: 10.4103/0974-2077.184043. PMID: 27398008
  26. Asai Y, Baibergenova A, Dutil M, et al. Management of acne: Canadian clinical practice guideline. CMAJ. 2016 Feb;188(2):118-126. doi: 10.1503/cmaj.140665. PMID: 26573753
  27. Eichenfield LF, Krakowski AC, Piggott C, et al; American Acne and Rosacea Society. Evidence-based recommendations for the diagnosis and treatment of pediatric acne. Pediatrics. 2013 May;131(Suppl 3):S163-186. doi: 10.1542/peds.2013-0490B. PMID: 23637225
  28. Nast A, Dréno B, Bettoli V, et al. European evidence-based (S3) guideline for the treatment of acne - update 2016 - short version. J Eur Acad Dermatol Venereol. 2016 Aug;30(8):1261-1268. doi: 10.1111/jdv.13776. PMID: 27514932
  29. Zaenglein AL, Pathy AL, Schlosser BJ, et al. Guidelines of care for the management of acne vulgaris. J Am Acad Dermatol. 2016 May;74(5):945-973.e33. doi: 10.1016/j.jaad.2015.12.037. PMID: 26897386
  30. Dover JS, Batra P. Light-based, adjunctive, and other therapies for acne vulgaris. UpToDate. https://www.uptodate.com. 26 Sep 2019.
  31. Graber E. Hormonal therapy for women with acne vulgaris. UpToDate. https://www.uptodate.com. 26 Sep 2019.
  32. Oon HH, Wong SN, Aw DCW, et al. Acne management guidelines by the Dermatological Society of Singapore. J Clin Aesthet Dermatol. 2019 Jul;12(7):34-50. PMID: 31531161
  33. Thiboutot DM, Dréno B, Abanmi A, et al. Practical management of acne for clinicians: An international consensus from the Global Alliance to Improve Outcomes in Acne. J Am Acad Dermatol. 2018 Feb;78(2)(Suppl 1):S1-S23.e1. doi: 10.1016/j.jaad.2017.09.078. PMID: 29127053
  34. Thiboutot D, Zaenglein A. Pathogenesis, clinical manifestations, and diagnosis of acne vulgaris. UpToDate. https://www.uptodate.com. 8 Oct 2019.
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