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ACNE VULGARIS
Acne vulgaris is a chronic inflammatory dermatosis which is notable for open and/or closed comedones (blackheads and whiteheads) and inflammatory lesions including papules, pustules or nodules.
Mild acne has <20 comedones or <15 inflammatory lesions or <30 total lesion count.
Moderate acne has 20-100 comedones or 15-20 inflammatory lesions or 30-125 total lesion count.
Severe papules/pustules or nodulocystic acne is the acne resistant to topical treatment or if scarring/nodular lesions are present.

Differential Diagnosis

  • Formation of comedones is inherent to the diagnosis of acne vulgaris and when not evident, the following diagnoses may be considered: Keratosis pilaris, perioral dermatitis, rosacea, folliculitis, miliaria, hidradenitis suppurativa
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Stephen Padilla, 24 Jun 2019
Two independent, phase III studies (PERFECT 1 and 2) have shown the efficacy and safety of trifarotene 50-μg/g cream in the treatment of moderate acne on the face and trunk.