A once-daily dose (OAD) of the selective phosphodiesterase 5 (PDE5) inhibitor tadalafil was as effective as an on-demand or as-needed (pro re nata [PRN]) regimen for erectile dysfunction (ED), according to a meta-analysis.
According to the Singapore National Registry of Diseases Office (NRDO), prostate cancer is the third most common cancer and the sixth most common cause of cancer-related deaths affecting men in Singapore. Dr Daniel Tan, radiation oncologist and medical director of Asian American Radiation Oncology at Gleneagles Hospital, Singapore, speaks to Roshini Claire Anthony on the importance of early detection of prostate cancer and the challenges associated with diagnosing and treating this condition.
Minimally invasive percutaneous nephrolithotomy (mini-PCNL) provided a substantially higher stone-free rate (SFR) for upper renal calculi management compared with retrograde intrarenal surgery (RIRS), according to a meta-analysis. However, mini-PCNL also entailed a higher incidence of postoperative complications.
Larotrectinib delivers durable response across diverse cancer types, including paediatric and adult cancers, according to an interim analysis of three ongoing trials presented at the ASCO 2017 Annual Meeting.
The addition of abiraterone acetate to first-line androgen deprivation therapy (ADT) resulted in a significant improvement in overall survival (OS) in men with prostate cancer, according to the findings of the LATITUDE* and STAMPEDE** trials presented at the annual meeting of the American Society of Clinical Oncology (ASCO 2017) held in Chicago, Illinois, US.
Patients are more likely to report muscle-related adverse effects (AEs) when they know they are on statins, but not when they have no idea whether they are given statin or placebo in a blinded trial, the ASCOT-LLA* study found, suggesting that clinicians should be aware of potential nocebo effects when prescribing statins.
New drug applications approved by US FDA as of 1 - 15 May 2017 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
Use of transcutaneous electrical nerve stimulation (TENS) in combination with oxybutynin in the treatment of urge incontinence in children is superior to both TENS and oxybutynin monotherapy in terms of efficacy, a study has shown. Treatment with TENS also helps reduce the risk of oxybutynin-induced elevated postvoid residual urine volume.
Patients with localized prostate cancer achieve similar functional and pathologic outcomes with robot-assisted laparoscopic prostatectomy (RALP) or open radical retropubic prostatectomy, early results of the first trial comparing the two techniques have shown.