Obesity is associated with greater risk for unfavourable pathological features in men with low risk prostate cancer who are eligible for active surveillance, according to a study. Obese men are likely to have transition zone cancer, which is related to unfavourable pathology findings in those with very low risk prostate cancer.
The intravesical installation of Bacillus Calmette-Guerin (BCG) and mitomycin C (MMC) is a safe and effective approach to nonmuscle-invasive bladder cancer (NMIBC) following transurethral resection (TUR), a new systematic review shows.
The use of spot urine appears to be unhelpful in estimating 24-hour urinary sodium excretion at the individual level due to its poor performance with regard to misclassification, according to a recent study.
There is no significant association between urine calcium and bone mineral density in a large cohort of calcium kidney stone formers, unlike in previous small cross-sectional studies, but there is a significant inverse relationship in oestrogen-untreated kidney stone formers only.
Use of tadalafil daily may lead to increased lean mass content in nonobese men, with the increase potentially linked to improved insulin secretion, estradiol reduction and enhanced endothelial function in vivo.
High pathologic tumour (pT) stage, high grade and high RENAL (radius, exophytic/endophytic properties, nearness of deepest tumor portion to collecting system or sinus, anterior/posterior, and location relative to polar line) score predict disease recurrence for kidney tumours after partial nephrectomy, a recent study has found. In addition, the pT stage and grade increase the risk of metastasis, while RENAL score is a predictor of local recurrence.
In patients with nocturnal urgency secondary to overactive bladder (OAB) and low nocturnal bladder capacity, a mismatch between nocturnal urine production and bladder capacity may predict response to treatment with fesoterodine, according to a study. Symptom improvement appears to be mediated by increases in typical rather than maximum nocturnal voided volumes and be associated with improved quality of life.
Older patients with overactive bladder (OAB) appear to have increased frailty compared with individuals seeking care for other nononcologic urologic diagnosis, with frailty being a significant predictor of OAB, a study has found.
The quantity of uric acid stones has significantly increased in recent decades, according to a recent study. There are proportionately more female calcium stone formers but not uric acid stone formers with time. Furthermore, the most prominent factor distinguishing uric acid from calcium stones is urinary pH.