Both denosumab and bisphosphonates enhance bone mineral density (BMD) in men with nonmetastatic prostate cancer who are receiving androgen deprivation therapy (ADT), according to a systematic review and meta-analysis. In addition, denosumab lowers the risk for radiographic vertebral fractures.
A recent study has shown that patients with panurothelial carcinoma who underwent radical cystectomy and then radical nephroureterectomy with locally advanced disease in a large proportion have poor prognosis.
A decline in prostate-specific antigen (PSA) levels is a significant predictor of better overall survival (OS) in highly pretreated patients with metastatic castration-resistant prostate cancer (mCRPC), a new retrospective study reveals.
Intravesical chondroitin sulphate is superior to intravesical hyaluronic acid in the treatment of bladder pain syndrome (BPS)/interstitial cystitis (IC), improving 24-hour frequency, nocturia and interstitial cystitis problem index, according to a study.
Intravesical gentamicin may effectively reduce the frequency of infections in adult patients who have multiple symptomatic urinary tract infections (UTIs) refractory to conventional treatment, with the treatment being well tolerated and showing no evidence of systemic absorption, according to a retrospective study.
Future research on urinary incontinence (UI) should focus on better phenotyping, early disease, risk factor identification, patient-centred research, incorporation of new technologies and prevention, suggests a recent study.
Testosterone therapy may improve sexual function, enhance mood and reduce depressive symptoms in men ≤65 years, according to the testosterone trials (TTs). However, no improvement in vitality or walking distance was seen.
According to the Singapore National Registry of Diseases Office (NRDO), prostate cancer is the third most common cancer and the sixth most common cause of cancer-related deaths affecting men in Singapore. Dr Daniel Tan, radiation oncologist and medical director of Asian American Radiation Oncology at Gleneagles Hospital, Singapore, speaks to Roshini Claire Anthony on the importance of early detection of prostate cancer and the challenges associated with diagnosing and treating this condition.