Most Read Articles
Elvira Manzano, Yesterday
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
07 Oct 2017
Women who follow a low-fat dietary pattern appear to have reduced breast cancer mortality, according to data from the Earlier Women’s Health Initiative Dietary Modification trial.
Pearl Toh, 5 days ago
Women with higher plasma tryptophan concentrations were less likely to have poor sleep quality during pregnancy, especially among those with anxiety symptoms, according to the GUSTO* study.
Pearl Toh, 11 Oct 2017
Clinical practice is an art guided by good science, and clinical practice guideline (CPG) is meant to guide in integrating the art and science of clinical practice for the long-term benefits of patients, said Dr Abdul Rashid Abdul Rahman, a consultant cardiovascular physician at An-Nur Specialist Hospital in Bangi, Malaysia, during the 13th Asian-Pacific Congress of Hypertension (APCH) held in Singapore.

VYC-17.5L effective, safe for nasolabial folds

07 Jul 2017

VYC-17.5L (17.5 mg/mL hyaluronic acid, 0.3 percent lidocaine) has a good 1-year safety and effectivity profile for the treatment of moderate and severe nasolabial folds (NLF), a new study reveals.

The 70 participants (mean age 49±10 years; 94 percent female) with NLFs showed significant improvement in the primary endpoint of NLF severity in the left (mean change, -0.8± 0.8) and right (mean change, -0.8±0.7) NLFs at 12 months compared with baseline (p<0.0001).

Improvements in left and right NLF severity were also significant after the final treatment (mean changes, -2.0 and -1.9, respectively), after 1 month (mean change, -1.7 and -1.8, respectively) and after 9 months (mean change, -1.3 and -1.2, respectively; p<0.001 for all).

Mean investigator satisfaction scores ranged from 4.0±1.0 to 4.6±0.6 out of a maximum of 5 scores, while patient confidence scores were significantly higher after treatment compared with baseline.

Majority (n=67; 82.1 percent) of the patients were able to return to normal daily activity within 24 hours; four reported requiring recovery of 4 to 8 days before returning to normal activity.

Out of a maximum pain rating of 10, mean ratings were 2.0±1.8 for either side immediately after treatment. Pain ratings decreased to 0.7±1.5 and 0.8±1.7 for the left and right sides, respectively, after 14 days.

Initial swelling scores were 1.7±1.6 for either side and decreased to 1.4±2.2 and 1.5±2.2 for the left and right sides, respectively, at day 14. Bruising scores were initially 0.3±0.9 for both sides; ratings increased to 0.5±1.3 and 0.9±1.9 for left and right sides, respectively, after 14 days.

Only two adverse events were reported: reduced sensitivity, swelling and redness around the mouth (n=1), and swelling in the injection area (n=1). Both symptoms were resolved. 

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Most Read Articles
Elvira Manzano, Yesterday
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
07 Oct 2017
Women who follow a low-fat dietary pattern appear to have reduced breast cancer mortality, according to data from the Earlier Women’s Health Initiative Dietary Modification trial.
Pearl Toh, 5 days ago
Women with higher plasma tryptophan concentrations were less likely to have poor sleep quality during pregnancy, especially among those with anxiety symptoms, according to the GUSTO* study.
Pearl Toh, 11 Oct 2017
Clinical practice is an art guided by good science, and clinical practice guideline (CPG) is meant to guide in integrating the art and science of clinical practice for the long-term benefits of patients, said Dr Abdul Rashid Abdul Rahman, a consultant cardiovascular physician at An-Nur Specialist Hospital in Bangi, Malaysia, during the 13th Asian-Pacific Congress of Hypertension (APCH) held in Singapore.