Most Read Articles
08 Oct 2017
Treatment with vismodegib does not appear to increase the risk of subsequent squamous cell carcinoma (SCC) in comparison with standard surgical treatment of basal cell carcinoma (BCC), a recent study suggests.
Stephen Padilla, 10 Oct 2017
Secukinumab has shown efficacy and safety for patients with extensive moderate-to-severe scalp psoriasis, according to a recent study.
09 Oct 2017
Use of voriconazole appears to increase the risk specifically for squamous cell carcinoma (SCC) in the allogeneic haematopoietic cell transplantation (HCT) population, according to a recent study.
27 Sep 2017
Poor sleep quality is not uncommon among patients with psoriatic disease, suggests a recent study. Poor sleep is associated with fatigue, anxiety and lower EQ-5D. It is also associated with actively inflamed joints in patients with psoriatic arthritis (PsA).

VTE common in patients with pemphigus

23 Jul 2017

Patients with pemphigus are prone to venous thromboembolism (VTE), even more so during the first year after diagnosis, according to a recent study.

To investigate the incidence and characteristics of VTE in patients with pemphigus, researchers conducted a retrospective study following a cohort of 172 patients with newly diagnosed pemphigus for the development of VTE.

VTE developed at a median of 4 months from pemphigus diagnosis in 10 patients (6 percent) over a mean follow-up time of 4 years. The first year saw the highest risk at five VTE events per 100 patient-years or a 5-percent risk of VTE for that first year.

Of the 10 patients who developed VTE, five had deep vein thrombosis, four had pulmonary embolisms and one had both. The risk of VTE was not associated with both age and gender.

Most patients had either hereditary or acquired VTE risk factors as the result of pemphigus treatments and their complications, including hospitalization, immobilization and infections.

“VTE risk must be assessed in all patients, especially when hospitalized, and thrombo-prophylaxis should be initiated in qualifying cases,” researchers said.

This study is limited by the use of existing health records, which restricted the assessment of asymptomatic VTE and VTE risk factors. In addition, the investigators failed to study the matched control population.

“VTE has been reported to be a significant cause of death in patients with pemphigus,” according to researchers.

Editor's Recommendations
Most Read Articles
08 Oct 2017
Treatment with vismodegib does not appear to increase the risk of subsequent squamous cell carcinoma (SCC) in comparison with standard surgical treatment of basal cell carcinoma (BCC), a recent study suggests.
Stephen Padilla, 10 Oct 2017
Secukinumab has shown efficacy and safety for patients with extensive moderate-to-severe scalp psoriasis, according to a recent study.
09 Oct 2017
Use of voriconazole appears to increase the risk specifically for squamous cell carcinoma (SCC) in the allogeneic haematopoietic cell transplantation (HCT) population, according to a recent study.
27 Sep 2017
Poor sleep quality is not uncommon among patients with psoriatic disease, suggests a recent study. Poor sleep is associated with fatigue, anxiety and lower EQ-5D. It is also associated with actively inflamed joints in patients with psoriatic arthritis (PsA).