Most Read Articles
Roshini Claire Anthony, 6 days ago

Treatment failure in osteoporosis remains a problem, even among patients who are treatment-adherent, according to a presentation at the recent meeting of the Asian Federation of Osteoporosis Societies (AFOS 2017), held in Kuala Lumpur, Malaysia. 

Elvira Manzano, 5 days ago
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
2 days ago
Breast cancer patients have notably different microbiomes in the local breast tissue and urinary tract, a recent study reveals. Particularly, species in the Methylobacterium genus are reduced in the local breast tissue while the urinary tract is enriched in gram-positive bacteria.
Pearl Toh, 13 Oct 2017
Women with higher plasma tryptophan concentrations were less likely to have poor sleep quality during pregnancy, especially among those with anxiety symptoms, according to the GUSTO* study.

Vascular involvement in MLKI lowers knee function

30 Sep 2017

Knee function is lower in multiligament knee injury (MLKI) patients with artery injury requiring bypass grafts compared with MLKI patients without vascular involvement, a new matched-cohort analysis finds.

The retrospective study included 16 MLKI patients with vascular injury that required bypass grafting (mean age 30.3 years) and a matched cohort of 32 MLKI patients without vascular involvement (mean age 31.4 years).

In terms of knee function, the mean Lysholm scores for the vascular injury and control cohorts were 62.5 (16 to 100) and 86.4 (51 to 100) points, respectively, with the difference reaching statistical significance (p=0.001).

Controls also scored significantly higher on the International Knee Documentation Committee (IKDC) scale with a mean score of 83.8 (35.6 to 100) points compared to the 59.7 (14.9 to 100) points of the vascular injury patients (p=0.002).

Excellent ratings in the IKDC and Lysholm scales were recorded for only 19 and 25 percent of the vascular cohort, respectively. This was notably lower than the 66 and 69 percent in the control cohort, respectively.

There were no significant differences between the two groups in terms of extension (p=0.7) and flexion (p=0.6) ranges of motion, knee stability, time to surgery (p=0.7), knee dislocation grade (p=1.0), and percentage with peroneal nerve injury (p=1.0).

While body mass index (BMI; p=0.53) was also similar between the two groups, a BMI of more than 30 kg/m2 was found to be a significant predictor for lower Lysholm (p=0.0008) and IKDC (p=0.0009) scores.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Rheumatology digital copy today!
DOWNLOAD
Editor's Recommendations
Most Read Articles
Roshini Claire Anthony, 6 days ago

Treatment failure in osteoporosis remains a problem, even among patients who are treatment-adherent, according to a presentation at the recent meeting of the Asian Federation of Osteoporosis Societies (AFOS 2017), held in Kuala Lumpur, Malaysia. 

Elvira Manzano, 5 days ago
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
2 days ago
Breast cancer patients have notably different microbiomes in the local breast tissue and urinary tract, a recent study reveals. Particularly, species in the Methylobacterium genus are reduced in the local breast tissue while the urinary tract is enriched in gram-positive bacteria.
Pearl Toh, 13 Oct 2017
Women with higher plasma tryptophan concentrations were less likely to have poor sleep quality during pregnancy, especially among those with anxiety symptoms, according to the GUSTO* study.