Strawberry intervention does not alter postprandial vascular function, dysmetabolism
Adding strawberry powder to a high-fat meal neither changes vascular function nor lessens postprandial metabolic derangements in triglycerides, glucose or insulin compared with the control meal, according to a recent study.
No significant differences were observed between the strawberry and control meals for any outcomes. Consumption of either meal significantly lowered the augmentation index at 2 and 4 hours (p<0.002) and significantly increased triglycerides, insulin and glucose at all time points (p<0.001) compared with baseline.
To determine whether strawberry intervention (40 g freeze-dried strawberry powder or 0.45 kg fresh strawberries) to a high-fat (50 g total fat) meal has an effect on postprandial vascular function, as well as triglyceride, glucose and insulin responses, researchers randomly assigned healthy, overweight or obese adults (mean body mass index 31 kg/m2; mean age 2 years; 17 men) to either a control meal or a strawberry meal.
To control for hormonal variations, researchers separated testing sessions by ≥1 week for men and ∼1 month for women. They also obtained blood samples before the mean and 0.5, 1, 2 and 4 hours postmeal. Using pulse waveform analysis, blood pressure and arterial stiffness indexes were measured at baseline and 2 and 4 hours after the meal.
According to researchers, further research is warranted to verify the efficacy of strawberries or other polyphenol-rich intervention on postprandial responses, and future studies must also consider the acute meal-induced improvements in measures of vascular function.
Postprandial dysmetabolism is defined as an exaggerated spike in triglycerides, glucose and insulin. It is known to increase the risk of cardiovascular disease by inducing oxidative stress, inflammation and endothelial dysfunction, researchers said, adding that polyphenol-rich foods like strawberries may attenuate these effects when they are incorporated into a high-fat, calorie-dense meal.