Most Read Articles
Elvira Manzano, 17 Oct 2017
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
2 days ago
Drinking coffee, whether caffeinated or decaffeinated, is associated with a reduced risk of cardiovascular disease (CVD) and ischaemic heart disease (IHD) mortality in patients with a prior myocardial infarction (MI), according to a recent study.
3 days ago
Breast cancer patients have notably different microbiomes in the local breast tissue and urinary tract, a recent study reveals. Particularly, species in the Methylobacterium genus are reduced in the local breast tissue while the urinary tract is enriched in gram-positive bacteria.
Tristan Manalac, 3 days ago
Statin use, particularly in smokers, obese patients and nondiabetics, has a strong and dose-dependent association with decreasing risk of pancreatic ductal adenocarcinoma (PDAC), according to a new study.

Storage time of red blood cells for transfusion does not affect risk of postoperative AF

26 Feb 2017

Compared with the usual intraoperative allogeneic transfusion of red blood cells, longer storage times of the red blood cells for allogeneic transfusion is not associated with increased postoperative atrial fibrillation (AF) following cardiac surgery, a new study has shown.

The study included 2,978 patients (mean age 66.4 years) receiving coronary artery bypass grafting or valve surgery. For inclusion, patients had to be above the age of 15 years. Those with a history of AF or flutter prior to the surgery were excluded.

The association between the risk of postoperative AF and transfusion of red blood cells on the day of the surgery was determined. Similarly, the association between length of time of storage of the red blood cells before transfusion and postoperative AF was also investigated.

Of the patients, 21 percent underwent transfusion of red blood cells on the day of the surgery. Furthermore, 25 percent developed postoperative AF.

Compared with patients who did not undergo transfusion, those who did were at a greater risk of postoperative AF (adjusted odds ratio [OR], 1.37; 95 percent CI, 1.11 to 1.69; p=0.004).

This risk showed dependence to dose. Those who received four to six units of red blood cells had an OR of 1.62 (1.02 to 2.42) compared with those who received only one to thee units.

Patients were then stratified according to whether they received red blood cells stored for <14 days (adjusted OR, 1.59; 1.23 to 2.06) or at least 14 days (adjusted OR, 1.24; 0.94 to 1.64). Comparisons with those who did not receive transfusion showed no significant difference.

Results thus show that using stored red blood cells, taking into account storage time, does not influence the development of postoperative AF after cardiac surgery.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
DOWNLOAD
Editor's Recommendations
Most Read Articles
Elvira Manzano, 17 Oct 2017
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
2 days ago
Drinking coffee, whether caffeinated or decaffeinated, is associated with a reduced risk of cardiovascular disease (CVD) and ischaemic heart disease (IHD) mortality in patients with a prior myocardial infarction (MI), according to a recent study.
3 days ago
Breast cancer patients have notably different microbiomes in the local breast tissue and urinary tract, a recent study reveals. Particularly, species in the Methylobacterium genus are reduced in the local breast tissue while the urinary tract is enriched in gram-positive bacteria.
Tristan Manalac, 3 days ago
Statin use, particularly in smokers, obese patients and nondiabetics, has a strong and dose-dependent association with decreasing risk of pancreatic ductal adenocarcinoma (PDAC), according to a new study.