Most Read Articles
5 days ago
Greater exposure to total volatile organic compounds (TVOCs) appears to have an adverse effect on early postnatal growth, according to a study.
01 Dec 2014

Q: Introduction to perimenopause – when it begins, what are the signs and symptoms?
A: Many women do not realize that menopause does not happen over 24 hours. For a period of 10 to 15 years before menopause is established at the average age of 51, a woman will already be undergoing a period of change in a phase of life known as perimenopause or ‘around menopause’. Perimenopause is typically experienced by women aged between 40 and 56.

18 Sep 2017
Functional capacity (FC) in active postmenopausal women depends more on lower limb muscle strength than on abdominal obesity, suggesting that those with abdominal obesity may not necessarily have a reduced FC as long as lower limb muscle strength is preserved, according to a study.
Robert Chin, 6 days ago
This review article outlines the prevalence of nausea and vomiting of pregnancy (NVP) and hyperemesis gravidarum (HG), definition of NVP and HG, aetiology, risk factors, complications of HG, recommended investigations, primary care management, hospital and ambulatory daycare, therapeutic management of HG supported by good clinical evidence, discharge planning, and importance of the multidisciplinary team to provide high quality care in patients with NVP and HG.

Standardized vs individualized oligomenorrhoea, amenorrhoea treatment using Chinese herbs

14 Feb 2017

Both standardized and individualized regimens of multiherb Chinese herbal medicine have comparable clinical efficacies and safeties when used to treat polycystic ovary syndrome-related amenorrhoea and oligomenorrhoea, a new study has shown.

The preliminary study involved 40 women between the ages of 18 and 40 years diagnosed with amenorrhea and oligomenorrhea. Those who were suspected to be pregnant, had other causes of menstrual irregularity actively trying to get pregnant, had a history of liver or kidney diseases or had a history of mental disorders were excluded.

The primary outcome was whether oligomenorrhea and amenorrhea were feasible as the main outcomes for randomized controlled trials. Effects of the treatment were evaluated according to safety, efficacy and acceptability.

Only 29 of the 40 participants were able to successfully complete the study. Hirsutism was the most common complaint reported, along with menstrual irregularity and weight.

Interestingly, after 6 months of the Chinese herbal medicine treatment, both standardized (mean difference [MD], 0.18±0.06; 95 percent CI, 0.06 to 0.29; p=0.0027) and individualized (MD, 0.27±0.06; 0.15 to 0.39; p<0.001) regimen groups reported significant in-group improvements in menstrual rate.

However, there was no reported significant difference in improvements between standardized and individualized treatments (p=0.26). Similarly, within-group improvements for hisrutism did not reach statistical significance when tested between groups.

There were no documented improvements in weight and BMI in either group. In terms of safety, kidney and liver function remained normal for both standardized and individualized regimens. Using a tablet for administration, as participant feedback suggested, might improve adherence.

The findings show that oligomenorrhea and amenorrhea are feasible outcomes for testing Chinese herbal medicine. Furthermore, primary findings imply efficacy, but without any difference between standardized and individualized treatment regimens.

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Most Read Articles
5 days ago
Greater exposure to total volatile organic compounds (TVOCs) appears to have an adverse effect on early postnatal growth, according to a study.
01 Dec 2014

Q: Introduction to perimenopause – when it begins, what are the signs and symptoms?
A: Many women do not realize that menopause does not happen over 24 hours. For a period of 10 to 15 years before menopause is established at the average age of 51, a woman will already be undergoing a period of change in a phase of life known as perimenopause or ‘around menopause’. Perimenopause is typically experienced by women aged between 40 and 56.

18 Sep 2017
Functional capacity (FC) in active postmenopausal women depends more on lower limb muscle strength than on abdominal obesity, suggesting that those with abdominal obesity may not necessarily have a reduced FC as long as lower limb muscle strength is preserved, according to a study.
Robert Chin, 6 days ago
This review article outlines the prevalence of nausea and vomiting of pregnancy (NVP) and hyperemesis gravidarum (HG), definition of NVP and HG, aetiology, risk factors, complications of HG, recommended investigations, primary care management, hospital and ambulatory daycare, therapeutic management of HG supported by good clinical evidence, discharge planning, and importance of the multidisciplinary team to provide high quality care in patients with NVP and HG.