Most Read Articles
3 years ago

Over the past few decades, there has been widespread concern about the increasing proportion of births born by caesarean delivery. The rising rate of primary caesarean section has led to the increased number of obstetric population with a history of prior caesarean delivery. Although this group of women may be offered planned vaginal birth after previous caesarean section (VBAC) or elective repeat caesarean section (ERCS), the VBAC rate is generally low particularly in well-developed countries. In the United States, the VBAC rate has decreased to 8.5% by 2006, while the total caesarean rate has increased to 31.1%.1

one year ago
Kidney and bladder stones (urinary tract stones) are not risk factors for osteoporosis in postmenopausal women, according to the women’s health initiative.
Lianne Cowie, 3 years ago

Tumor necrosis factor (TNF)-α inhibitors are commonly used in the treatment of inflammatory bowel disease (IBD), but the effects of these agents on pregnancy outcomes remain unclear. Now, a systematic review of the English literature has indicated that they pose little risk to the mother or her infant, even if use is continued through the third trimester.

one year ago
A study on participants from the Women's Health Initiative showed the dissociation between calcium/vitamin D supplementation and reduction in menopausal symptoms.

Standardized vs individualized oligomenorrhoea, amenorrhoea treatment using Chinese herbs

3 months ago

Both standardized and individualized regimens of multiherb Chinese herbal medicine have comparable clinical efficacies and safeties when used to treat polycystic ovary syndrome-related amenorrhoea and oligomenorrhoea, a new study has shown.

The preliminary study involved 40 women between the ages of 18 and 40 years diagnosed with amenorrhea and oligomenorrhea. Those who were suspected to be pregnant, had other causes of menstrual irregularity actively trying to get pregnant, had a history of liver or kidney diseases or had a history of mental disorders were excluded.

The primary outcome was whether oligomenorrhea and amenorrhea were feasible as the main outcomes for randomized controlled trials. Effects of the treatment were evaluated according to safety, efficacy and acceptability.

Only 29 of the 40 participants were able to successfully complete the study. Hirsutism was the most common complaint reported, along with menstrual irregularity and weight.

Interestingly, after 6 months of the Chinese herbal medicine treatment, both standardized (mean difference [MD], 0.18±0.06; 95 percent CI, 0.06 to 0.29; p=0.0027) and individualized (MD, 0.27±0.06; 0.15 to 0.39; p<0.001) regimen groups reported significant in-group improvements in menstrual rate.

However, there was no reported significant difference in improvements between standardized and individualized treatments (p=0.26). Similarly, within-group improvements for hisrutism did not reach statistical significance when tested between groups.

There were no documented improvements in weight and BMI in either group. In terms of safety, kidney and liver function remained normal for both standardized and individualized regimens. Using a tablet for administration, as participant feedback suggested, might improve adherence.

The findings show that oligomenorrhea and amenorrhea are feasible outcomes for testing Chinese herbal medicine. Furthermore, primary findings imply efficacy, but without any difference between standardized and individualized treatment regimens.

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Most Read Articles
3 years ago

Over the past few decades, there has been widespread concern about the increasing proportion of births born by caesarean delivery. The rising rate of primary caesarean section has led to the increased number of obstetric population with a history of prior caesarean delivery. Although this group of women may be offered planned vaginal birth after previous caesarean section (VBAC) or elective repeat caesarean section (ERCS), the VBAC rate is generally low particularly in well-developed countries. In the United States, the VBAC rate has decreased to 8.5% by 2006, while the total caesarean rate has increased to 31.1%.1

one year ago
Kidney and bladder stones (urinary tract stones) are not risk factors for osteoporosis in postmenopausal women, according to the women’s health initiative.
Lianne Cowie, 3 years ago

Tumor necrosis factor (TNF)-α inhibitors are commonly used in the treatment of inflammatory bowel disease (IBD), but the effects of these agents on pregnancy outcomes remain unclear. Now, a systematic review of the English literature has indicated that they pose little risk to the mother or her infant, even if use is continued through the third trimester.

one year ago
A study on participants from the Women's Health Initiative showed the dissociation between calcium/vitamin D supplementation and reduction in menopausal symptoms.