Most Read Articles
Elvira Manzano, 2 days ago
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
07 Oct 2017
Women who follow a low-fat dietary pattern appear to have reduced breast cancer mortality, according to data from the Earlier Women’s Health Initiative Dietary Modification trial.
Pearl Toh, 6 days ago
Women with higher plasma tryptophan concentrations were less likely to have poor sleep quality during pregnancy, especially among those with anxiety symptoms, according to the GUSTO* study.
4 days ago
Second eye cataract surgery provides greater improvement in visual function and quality of life compared with first eye cataract surgery alone, a recent study claims.

SPLS delivers comparable safety outcomes on obese, nonobese colorectal cancer patients

23 Aug 2017

There is no apparent difference in safety outcomes of single-port laparoscopic surgery (SPLS) between obese and nonobese colorectal cancer patients, a new retrospective cohort study has found.

“Hence, SPLS can be safely recommended for colorectal cancer in obese patients if the surgeon is experienced. Nevertheless, the technique used warrants further investigation, and a large-scale prospective study is required,” researchers said.

The study included 323 colorectal cancer patients who received SPLS. Only those ≥18 years of age and with malignancies in the colon or rectum were included. Exclusion criteria were emergency SPLS and resection of other organs.

Participants were stratified into three according to BMI: nonobese (BMI <25.0 kg/m2; n=2323), obese I (BMI 25.0 to 29.9 kg/m2; n=80) and obese II (BMI ≥30.0 kg/m2; n=10). Outcomes were 30-day reoperation, 30-day mortality and adverse events within 30 days of operation.

The mean operation time in nonobese patients (269.2±110.2 minutes) was not significantly different than in obese I (270.4±81.7 minutes) and obese II (342.8±182.6 minutes; p=0.247) patients. There were also no significant differences in estimated surgical blood loss among the three groups (277.7±208.5 vs 260.5±209.2 vs 387.0±278.3, respectively; p=0.205).

Mortality (p=0.404) and conversion (p=0.937) rates were also comparable in nonobese (0.9 percent for both), obese I (0 and 1.3 percent, respectively) and obese II (0 percent for both) patients.

Time to flatus was significantly different among the three groups (2.2±1.7 vs 2.0±1.8 vs 3.0±1.6 for nonobese, obese I and obese II patients, respectively; p=0.04).

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Most Read Articles
Elvira Manzano, 2 days ago
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
07 Oct 2017
Women who follow a low-fat dietary pattern appear to have reduced breast cancer mortality, according to data from the Earlier Women’s Health Initiative Dietary Modification trial.
Pearl Toh, 6 days ago
Women with higher plasma tryptophan concentrations were less likely to have poor sleep quality during pregnancy, especially among those with anxiety symptoms, according to the GUSTO* study.
4 days ago
Second eye cataract surgery provides greater improvement in visual function and quality of life compared with first eye cataract surgery alone, a recent study claims.