Most Read Articles
Roshini Claire Anthony, 11 Oct 2017

The prevalence of resistant hypertension may be lower than expected, particularly once pseudo-resistant hypertension due to treatment nonadherence is taken into account, according to a presentation at the recent APCH 2017.

Pank Jit Sin, 07 Jan 2015

Cardiovascular diseases (CVD) have been the main cause of death in the Malaysian population since 2007. This trend has continued, with the number of people dying from CVD-related causes increasing year on year. 

Tristan Manalac, 12 Oct 2017
Administration of a long-acting medication at the time that is most suitable for maximum patient compliance is the best approach in controlling blood pressure, said Dr. Trefor Morgan at the recently concluded 13th Asian-Pacific Congress of Hypertension (APCH 2017), held at the Suntec Singapore Convention and Exhibition Centre.
Elaine Soliven, 11 Oct 2017
Reducing daily salt intake is associated with improved blood pressure (BP) levels in patients with hypertension, according to a study presented at APCH 2017.

Serum resistin predicts aortic stiffness in coronary artery disease

01 Sep 2017

Serum concentrations of resistin is a biomarker for aortic stiffness in patients with coronary artery disease (CAD), a recent study from Taiwan has shown.

The aortic stiffness of 104 CAD patients (mean age 65.63±9.17 years; 75 percent male) was measured using carotid-femoral pulse wave velocity. Those with acute myocardial infarction, pulmonary oedema, acute infections or were taking calcium, bisphosphonates or oestrogens were excluded.

Fasting blood samples were collected from the participants and were subjected to laboratory tests to measure levels of blood urea nitrogen (BUN), high- and low-density lipoprotein (HDL, LDL) and high-sensitivity C-reactive protein (hs-CRP).

Of the participants, 35.6 percent (n=37) had high aortic stiffness. Diabetes mellitus was more common in patients with high aortic stiffness (p=0.001).

Serum resistin levels were significantly higher in patients with both CAD and diabetes mellitus than in those without the diabetes comorbidity (p=0.003). Resistin levels were not significantly different with respect to the presence of the hypertension comorbidity.

Multivariate forward stepwise linear regression analysis showed that diabetes mellitus (β, 0.239; p=0.006), waist circumference (β, 0.384; p<0.001) and age (β, 0.203; p=0.019) were all significant predictors of resistin concentrations in CAD patients.

Subsequent multivariate logistic regression showed that higher serum resistin (odds ratio [OR], 1.275; 95 percent CI, 1.065 to 1.527; p=0.008), diabetes mellitus (OR, 4.906; 1.418 to 16.970; p=0.012), older age (OR, 1.089; 1.005 to 1.180; p=0.036) and higher hs-CRP (OR, 1.226; 1.010 to 1.486; p=0.039) were independent predictors of aortic stiffness in CAD patients.

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Most Read Articles
Roshini Claire Anthony, 11 Oct 2017

The prevalence of resistant hypertension may be lower than expected, particularly once pseudo-resistant hypertension due to treatment nonadherence is taken into account, according to a presentation at the recent APCH 2017.

Pank Jit Sin, 07 Jan 2015

Cardiovascular diseases (CVD) have been the main cause of death in the Malaysian population since 2007. This trend has continued, with the number of people dying from CVD-related causes increasing year on year. 

Tristan Manalac, 12 Oct 2017
Administration of a long-acting medication at the time that is most suitable for maximum patient compliance is the best approach in controlling blood pressure, said Dr. Trefor Morgan at the recently concluded 13th Asian-Pacific Congress of Hypertension (APCH 2017), held at the Suntec Singapore Convention and Exhibition Centre.
Elaine Soliven, 11 Oct 2017
Reducing daily salt intake is associated with improved blood pressure (BP) levels in patients with hypertension, according to a study presented at APCH 2017.