Most Read Articles
2 days ago
Overall survival (OS) and head and neck cancer (HNC)-specific survival vary among HNC sites, according to a study. In particular, cigarette smoking is a prognostic factor of OS and HNC-specific survival in patients with cancer of the oral cavity and oropharynx, whereas alcohol consumption is a prognostic factor of both survival outcomes in patients with cancer of the larynx.
18 Sep 2017
The additional use of intermittent low-energy diet (LED) or daily meal replacements after a mean 10-percent weight loss and 1-year maintenance effectively maintains weight loss in obese patients with knee osteoarthritis for 3 years, according to a recent study.
3 days ago
Adiponectin, but not leptin, is significantly correlated with proteinuria and its severity in systemic lupus erythematosus (SLE) nephritis, reveals a new cross-sectional study.
Jairia Dela Cruz, 3 days ago
Laparoscopic sleeve gastrectomy (SG) appears to be effective in Asians, with early weight loss correlating with midterm weight maintenance and remission of obesity-related comorbidities 1 year after the surgery, according to a study.

Sarcopenia linked to depression

14 Jul 2017

Sarcopenia appears to be independently associated with depression, according to a systematic review and meta-analysis.

Researchers searched multiple electronic literature databases for observational studies investigating the relationship between sarcopenia and depression. A total of 15 articles were included.

Ten studies reported an association between sarcopenia and depression (crude odds ratio [OR], 1.640; 95 percent CI, 1.247 to 2.155). This association was retained after adjusting for potential confounders such as age, gender, cognitive performance and physical activity (adjusted OR, 1.821; 1.160 to 2.859).

A stratified analysis demonstrated that the studies using bioelectrical impedance analysis for measurement of body composition tended to report an elevated association between sarcopenia and depression compared with those that used dual-energy X-ray absorptiometry or equation estimation.

Known as “poverty of flesh,” sarcopenia occurs in ageing and is characterized by a progressive deterioration in the mass, strength and function of muscle tissue. Such deteriorations have been reported to induce serious health consequences, with sarcopenia said to be the main driver of the decreased independence and quality of life associated with ageing. [J Am Geriatr Soc 2002;50:889–96]

Potential mechanisms linking sarcopenia and common mental disorders involve (1) neurotrophins, which promote neuronal survival, driving neurogenesis in the hippocampus, which is a key region of the brain implicated in psychiatric illness; and (2) inflammation and oxidative stress. [Curr Osteoporos Rep 2015;13:351-7]

Health recommendations across the life course should focus on the achievement of optimal peak muscle mass and performance, as well as a slowing or reversal of age-related muscle deterioration, to reduce the burden of disability and frailty in later life. [J Nutr Health Aging 2000;4:140–2; Curr Aging Sci 2011;3:90–101]

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Most Read Articles
2 days ago
Overall survival (OS) and head and neck cancer (HNC)-specific survival vary among HNC sites, according to a study. In particular, cigarette smoking is a prognostic factor of OS and HNC-specific survival in patients with cancer of the oral cavity and oropharynx, whereas alcohol consumption is a prognostic factor of both survival outcomes in patients with cancer of the larynx.
18 Sep 2017
The additional use of intermittent low-energy diet (LED) or daily meal replacements after a mean 10-percent weight loss and 1-year maintenance effectively maintains weight loss in obese patients with knee osteoarthritis for 3 years, according to a recent study.
3 days ago
Adiponectin, but not leptin, is significantly correlated with proteinuria and its severity in systemic lupus erythematosus (SLE) nephritis, reveals a new cross-sectional study.
Jairia Dela Cruz, 3 days ago
Laparoscopic sleeve gastrectomy (SG) appears to be effective in Asians, with early weight loss correlating with midterm weight maintenance and remission of obesity-related comorbidities 1 year after the surgery, according to a study.