Rotating shift work may increase risk of hypertension
Shift work status appears to influence the development of hypertension, according to a recent study. Rotating shift work is more likely to increase the risk of high blood pressure, but no significant association exists between night shift status and hypertension.
In this systematic review and meta-analysis, researchers performed a literature search using Medline, Embase and Cochrane Database from inception through October 2016. Those included were articles (Nine cohort and 18 cross-sectional studies) that reported odds ratios (ORs) comparing the risk of hypertension in shift workers.
Also, there was a prespecified subgroup analysis by rotating shift and night shift statuses. A random-effect, generic inverse variance method was used to calculate pooled OR and 95 percent CI.
The observational studies involved a total of 394,793 individuals. The pooled OR of hypertension in shift workers was 1.31 (95 percent CI, 1.07 to 1.60) in cohort and 1.10 (1.00 to 1.20) in cross-sectional studies.
Upon restriction of the meta-analysis only to cohort studies in the rotating shift, the pooled OR of hypertension in rotating shift workers was 1.34 (1.08 to 1.67). The data was limited with respect to night shift and hypertension in cohort studies. Finally, night shift workers in cross-sectional studies had a pooled hypertension OR of 1.07 (0.85 to 1.35).
A prior meta-analysis of nine observational studies including 112,267 individuals revealed that daytime napping was significantly associated with hypertension. When meta-analysis was limited only to studies assessing the risk of hypertension in daytime nappers, the pooled risk ratio of hypertension was 1.19 (1.06 to 1.35). [J Evid Based Med 2016;9:205-212]