Most Read Articles
5 days ago
Obesity has a slight and substantial negative impact on the cognitive functioning of healthy individuals and major depressive disorder patients (MDD), respectively, a new study shows.
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Chronic obstructive pulmonary disease (COPD) is currently the 10th commonest cause of death in Singapore, with a disease burden of 5.9 percent according to a 2015 population-based survey (EPIC-Asia survey) in Singapore. Pearl Toh spoke with Dr Augustine Tee, chief and senior consultant of the Department of Respiratory and Critical Care Medicine at Changi General Hospital (CGH) in Singapore, on how COPD is often underdetected in the primary care population as symptoms are not specific and diagnosis requires a combination of clinical risk factors, symptoms and spirometry testing.

Risk of migraine in adulthood increased among males who suffer from growth restriction in utero

10 days ago
Males who suffer from growth restriction in utero appear to be at increased risk of developing migraine in adulthood, according to a recent study in Norway.

In the population-based Nord-Trøn-delag Health Study (HUNT 3), a validated headache questionnaire that differentiated between migraine and tension-type headache was administered to 4,557 females and 2,789 males aged 19–41 years. Responses were linked with data on weight and gestational age at birth obtained from the Norwegian Medical Birth Registry, and participants were categorized as appropriate for gestational age (AGA), small for gestational age (SGA), or very small for gestational age (VSGA).

A significant association between growth restriction in utero and migraine was noted among males (p<0.001), but not females (p=0.20). Males in the VSGA category, in particular, were at increased risk of migraine (odds ratio [OR], 2.73, 95 percent confidence interval [CI], 1.63–4.58; p<0.001), while those categorized as SGA had an intermediate risk (OR, 1.50, 95 percent CI, 0.96–2.35; p=0.08) compared with males in the AGA category. No association between growth restriction and frequency of tension-type headache was noted for either gender.

These findings suggest that migraine is at least partly influenced by early life events and that males are particularly vulnerable, said the researchers.
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Most Read Articles
5 days ago
Obesity has a slight and substantial negative impact on the cognitive functioning of healthy individuals and major depressive disorder patients (MDD), respectively, a new study shows.
9 days ago
Increased serum levels of C-X-C motif chemokine (CXCL)-11, CXCL-9, CXCL-10 and interferon (IFN)-γ are associated with clinical manifestations of adult-onset Still’s disease (AOSD), reports a new study.
3 days ago
Myopia is associated with depressive symptoms in Chinese adults, a new population-based study shows.
4 days ago
Chronic obstructive pulmonary disease (COPD) is currently the 10th commonest cause of death in Singapore, with a disease burden of 5.9 percent according to a 2015 population-based survey (EPIC-Asia survey) in Singapore. Pearl Toh spoke with Dr Augustine Tee, chief and senior consultant of the Department of Respiratory and Critical Care Medicine at Changi General Hospital (CGH) in Singapore, on how COPD is often underdetected in the primary care population as symptoms are not specific and diagnosis requires a combination of clinical risk factors, symptoms and spirometry testing.