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Repeated yearly exposure to exercise training improves BP, MetS evolution

19 Sep 2017

There is a need for at least 2 consecutive years of 4-month aerobic interval training to chronically enhance metabolic syndrome (MetS; z score), a recent study has found. Blood pressure (BP) that does not fully revert to pretraining values mediates this chronic effect, allowing a cumulative improvement.

“On the other hand, sedentarism in MetS patients during 3 years increases their predicted atherosclerotic diseases risk,” researchers said.

In this study that sought to determine whether repeated yearly training programmes consolidate the transient BP improvements of one exercise programme into durable adaptations, obese middle-age individuals with MetS went through high-intensity aerobic interval training during 16 weeks in 3 consecutive years (training group [TRAIN]; n=23).

Researchers then compared the evolution of MetS components with a matched-group that remained sedentary (control group [CONT]; n=26).

TRAIN reduced systolic arterial pressure (‒8.5±2.5 mm Hg), blood glucose (‒19.9±2.6 mg/dl), waist circumference (‒3.8±0.1 cm) and MetS z score (‒0.3±0.1) below CONT (p<0.05 for all) at the end of the first training programme (0 to 4 months). With detraining (month 4 to 12) TRAIN adaptations returned to baseline levels (month 0) except for BP.

After the second exercise programme (month 12 to 16), TRAIN lowered blood glucose (‒19.0±2.0 mg/dl) and waist circumference (‒4.1±0.1 cm) below CONT. Blood glucose, BP and z score started below CONT values after detraining (‒6.8±0.9 mm Hg; ‒24.6±2.5 mg/dl and ‒0.4±0.05, respectively; p<0.05 for all). These differences grew wider with the last training programme (month 24 to 28).

Only in CONT did the 10-year risk estimation of atherosclerotic cardiovascular disease increased (8.6±1.1 to 10.1±1.3 percent; year 2 to 3; p<0.05).

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Most Read Articles
Roshini Claire Anthony, 6 days ago

Treatment failure in osteoporosis remains a problem, even among patients who are treatment-adherent, according to a presentation at the recent meeting of the Asian Federation of Osteoporosis Societies (AFOS 2017), held in Kuala Lumpur, Malaysia. 

Elvira Manzano, 5 days ago
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
2 days ago
Breast cancer patients have notably different microbiomes in the local breast tissue and urinary tract, a recent study reveals. Particularly, species in the Methylobacterium genus are reduced in the local breast tissue while the urinary tract is enriched in gram-positive bacteria.
Pearl Toh, 13 Oct 2017
Women with higher plasma tryptophan concentrations were less likely to have poor sleep quality during pregnancy, especially among those with anxiety symptoms, according to the GUSTO* study.