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Rates of diabetic retinopathy, VTDR high among Indonesians with T2D

18 days ago

Both diabetic retinopathy (DR) and vision-threatening DR (VTDR) are common in Indonesian adults with type 2 diabetes (T2D), a new population-based cross-sectional study reveals.

Specifically, around 25 percent of adults with diabetes had VTDR, while at least 4 percent of individuals with VTDR had bilateral blindness.

In a population of 1,184 Indonesian adults above (aged >30 years) with T2D, the prevalence of DR was 43.1 percent (95 percent CI, 39.6 to 46.6) while that of VTDR was 26.3 (23.1 to 29.5) percent.

Compared to those in rural areas, the prevalence of DR (46.2 vs 36.6 percent) and VTDR (29.6 vs 19.5 percent) were significantly higher in adults in urban areas (p<0.001 for both). In contrast, there was no difference in DR prevalence between males and females (40.3 vs 44.3 percent, respectively).

After controlling for confounders, a long duration of diabetes (odds ratio [OR], 2.61; 95 percent CI, 1.24 to 5.51; p for trend<0.001), hypertension (OR, 1.52; 1.19 to 1.93; p<0.001) and a history of foot ulcers (OR, 2.00; 1.42 to 2.82; p=0.007) were all significantly associated with DR.

Similarly, a long diabetes duration (OR, 3.24; 1.53 to 6.83; p for trend<0.001), hypertension (OR, 1.72; 1.29 to 2.27; p=0.028) and a history of foot ulcers (OR, 3.23; 2.24 to 4.68; p<0.001) were also associated with the risk of VTDR after controlling for confounders.

Among patient with DR and VTDR, 4.7 and 6.9 percent, respectively, had bilateral severe visual impairment. After controlling for cataract cases, the prevalence rates of bilateral blindness in the DR and VTDR patients were 2.34 and 4.4 percent, respectively.

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