Most Read Articles
3 days ago
Higher circulating levels of docosahexaenoic acid (DHA) and docosapentaenoic acid (DPA) appear to be protective against incident atherothrombotic and cardioembolic strokes, respectively, according to a recent study.
Roshini Claire Anthony, 5 days ago

The prevalence of resistant hypertension may be lower than expected, particularly once pseudo-resistant hypertension due to treatment nonadherence is taken into account, according to a presentation at the recent APCH 2017.

Pank Jit Sin, 07 Jan 2015

Cardiovascular diseases (CVD) have been the main cause of death in the Malaysian population since 2007. This trend has continued, with the number of people dying from CVD-related causes increasing year on year. 

Tristan Manalac, 5 days ago
Administration of a long-acting medication at the time that is most suitable for maximum patient compliance is the best approach in controlling blood pressure, said Dr. Trefor Morgan at the recently concluded 13th Asian-Pacific Congress of Hypertension (APCH 2017), held at the Suntec Singapore Convention and Exhibition Centre.

Pulse pressure linked to long-term stroke outcomes among older patients

21 Aug 2017

There appears to be a significant association between pulse pressure (PP) and long-term stroke outcomes, and this relationship is evident among patients aged older than 60 years, a study has found.

Researchers looked at 4,195 patients (mean age 61.2 years; 68.4 percent male) with first-ever ischaemic stroke within 3 months of enrolment from The Standard Medical Management in Secondary Prevention of Ischemic Stroke in China (SMART) II study. The patients were stratified by age (<60 and ≥60 years) and had their baseline blood pressure (BP) measured. Study endpoints included the combined endpoints of recurrent vascular events and all-cause mortality, and recurrent stroke.

In the <60 years age group, BP components (systolic [S]BP, diastolic [D]BP, mean arterial pressure [MAP] and PP) had no significant association with long-term stroke outcomes. In the ≥60 years age group, PP was significantly related with the combined endpoints (hazards ratio [HR], 1.35; 95 percent CI, 1.18 to 1.54) and recurrent stroke (HR, 1.46; 1.24 to 1.72).

When dual BP components of SBP and PP, DBP and PP, or MAP and PP were analysed, SBP, DBP or MAP did not provide incremental value for predicting long-term stroke outcomes.

The present data indicate that PP within 3 months after ischaemic stroke is associated with 2-year outcomes of the combined endpoints and recurrent stroke among patients aged older than 60 years. Researchers noted that for every 1-SD increase in PP, there was a 35-percent increase in the risk of recurrent vascular events and all-cause mortality and a 46-percent increase in the risk of recurrent stroke.

“Higher PP, considered as an indicator or consequence of aortic stiffening, might [worsen] the long-term prognosis under stroke conditions,” researchers said.

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Most Read Articles
3 days ago
Higher circulating levels of docosahexaenoic acid (DHA) and docosapentaenoic acid (DPA) appear to be protective against incident atherothrombotic and cardioembolic strokes, respectively, according to a recent study.
Roshini Claire Anthony, 5 days ago

The prevalence of resistant hypertension may be lower than expected, particularly once pseudo-resistant hypertension due to treatment nonadherence is taken into account, according to a presentation at the recent APCH 2017.

Pank Jit Sin, 07 Jan 2015

Cardiovascular diseases (CVD) have been the main cause of death in the Malaysian population since 2007. This trend has continued, with the number of people dying from CVD-related causes increasing year on year. 

Tristan Manalac, 5 days ago
Administration of a long-acting medication at the time that is most suitable for maximum patient compliance is the best approach in controlling blood pressure, said Dr. Trefor Morgan at the recently concluded 13th Asian-Pacific Congress of Hypertension (APCH 2017), held at the Suntec Singapore Convention and Exhibition Centre.